Date published: 2026-5-30

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ZNF518B Activators

The class of chemicals known as ZNF518B activators encompasses a diverse group of molecules that can regulate gene expression and modulate signaling pathways within cells. These activators can influence the activity of transcription factors, which are proteins that play a critical role in converting DNA sequences into functional products. They achieve this by binding to specific DNA sequences and either promoting or suppressing the transcription of genes. The activation of ZNF518B, a zinc finger protein, can have cascading effects within the cellular milieu, as zinc finger proteins are known to be pivotal in the orchestration of developmental processes and maintenance of cellular functions. By altering the transcriptional landscape, ZNF518B activators can indirectly affect the expression of various genes, including those directly regulated by ZNF518B.

The chemical activators of ZNF518B can affect chromatin structure and epigenetics, which in turn can facilitate or hinder the binding of transcription factors to their target DNA sequences. By inhibiting enzymes like DNA methyltransferases and histone deacetylases, these chemicals can promote a more relaxed chromatin state, enhancing gene transcription. Similarly, compounds that modulate intracellular signaling pathways can activate kinase cascades, ultimately affecting transcription factor activity. For example, the modulation of cAMP levels within the cell can lead to the activation of protein kinase A, which can phosphorylate transcription factors and affect their ability to regulate gene expression. Through these diverse mechanisms, ZNF518B activators can exert influence over the protein's function and its role in the regulation of genetic pathways.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A molecule that regulates gene expression and can modulate the transcription of genes that are targets of ZNF518B, or that regulate ZNF518B itself.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

An activator of adenylate cyclase that increases cAMP levels and can activate protein kinase A (PKA), possibly influencing transcription factors that regulate ZNF518B.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

An activator of protein kinase C (PKC) that can initiate signaling cascades, potentially leading to the activation of transcription factors that regulate ZNF518B.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A polyphenol that modulates multiple signaling pathways and can alter the activity of transcription factors, possibly affecting ZNF518B.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A compound that activates sirtuins and can affect the acetylation status of transcription factors, potentially influencing ZNF518B expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

A modulator of various signaling pathways, which can alter transcriptional regulation activities, possibly affecting ZNF518B.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

A compound known to affect NF-κB, a transcription factor that can interact with or regulate the expression of ZNF518B.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A histone deacetylase inhibitor that can cause changes in chromatin structure, possibly affecting the binding of transcription factors to DNA regions regulating ZNF518B.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

A GSK-3 inhibitor that influences Wnt signaling, potentially impacting transcription factors that regulate ZNF518B expression.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$116.00
$179.00
$265.00
$369.00
$629.00
$1150.00
(1)

A cAMP analog that can activate PKA, potentially influencing phosphorylation of transcription factors that regulate ZNF518B.