Date published: 2025-12-5

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XRN Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of XRN Antibodies for advanced research in molecular biology. XRN Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). XRN proteins are essential components in RNA metabolism, particularly in the degradation of RNA molecules, maintaining cellular RNA homeostasis and regulating gene expression. The role of XRN proteins extends to mRNA turnover and cellular stress response mechanisms, making them significant targets in understanding various biological pathways and diseases. Researchers worldwide utilize XRN monoclonal antibodies to investigate RNA degradation pathways and their impact on gene regulation. Advanced research techniques supported by XRN monoclonal antibodies enable detailed analysis of RNA processing mechanisms and their influence on cellular function. Understanding XRN protein activity provides valuable insights into RNA quality control and decay pathways. Santa Cruz Biotechnology monoclonal antibodies for XRN proteins support researchers in advancing scientific knowledge of RNA biology and disease mechanisms.

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XRN Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

XRN1 Antibody (C-1)

sc-165985mouse IgG1 κ301-450 (h)WB, IP, IF, ELISAm, r, h
11
(5)

XRN1 Antibody (G-2)

sc-165984mouse IgG1 κ301-450 (h)WB, IP, IF, ELISAm, r, h
1
(1)

XRN2 Antibody (H-3)

sc-365258mouse IgG1 κ651-950 (h)WB, IP, IF, IHC(P), ELISAm, r, h
12
(6)

XRN CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRN1 CRISPR/Cas9 KO Plasmid (h)

sc-401910hGene KnockoutGFP0
(0)

XRN1 HDR Plasmid (h)

sc-401910-HDRhHomology Directed RepairPuromycin0
(0)

XRN1 Double Nickase Plasmid (h)

sc-401910-NIChGene KnockoutPuromycin0
(0)

XRN1 Double Nickase Plasmid (h2)

sc-401910-NIC-2hGene KnockoutPuromycin0
(0)

XRN1 CRISPR/Cas9 KO Plasmid (m)

sc-423993mGene KnockoutGFP0
(0)

XRN1 HDR Plasmid (m)

sc-423993-HDRmHomology Directed RepairPuromycin0
(0)

XRN1 Double Nickase Plasmid (m)

sc-423993-NICmGene KnockoutPuromycin0
(0)

XRN1 Double Nickase Plasmid (m2)

sc-423993-NIC-2mGene KnockoutPuromycin0
(0)

XRN2 CRISPR/Cas9 KO Plasmid (h2)

sc-411608-KO-2humanGene KnockoutGFP0
(0)

XRN2 HDR Plasmid (h2)

sc-411608-HDR-2humanHomology Directed RepairPuromycin0
(0)

XRN2 Double Nickase Plasmid (h)

sc-411608-NIChGene KnockoutPuromycin0
(0)

XRN2 Double Nickase Plasmid (h2)

sc-411608-NIC-2hGene KnockoutPuromycin0
(0)

XRN2 CRISPR/Cas9 KO Plasmid (m)

sc-423994mGene KnockoutGFP0
(0)

XRN2 HDR Plasmid (m)

sc-423994-HDRmHomology Directed RepairPuromycin0
(0)

XRN2 Double Nickase Plasmid (m)

sc-423994-NICmGene KnockoutPuromycin0
(0)

XRN2 Double Nickase Plasmid (m2)

sc-423994-NIC-2mGene KnockoutPuromycin0
(0)

XRN CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRN1 CRISPR Activation Plasmid (h)

sc-401910-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRN1 CRISPR Activation Plasmid (h2)

sc-401910-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRN1 Lentiviral Activation Particles (h)

sc-401910-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRN1 Lentiviral Activation Particles (h2)

sc-401910-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRN1 CRISPR Activation Plasmid (m)

sc-423993-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRN1 CRISPR Activation Plasmid (m2)

sc-423993-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRN1 Lentiviral Activation Particles (m)

sc-423993-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRN1 Lentiviral Activation Particles (m2)

sc-423993-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRN2 CRISPR Activation Plasmid (h)

sc-411608-ACThGene ActivationPuro, Blast, Hygro0
(0)

XRN2 CRISPR Activation Plasmid (h2)

sc-411608-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

XRN2 Lentiviral Activation Particles (h)

sc-411608-LAChGene ActivationPuro, Blast, Hygro0
(0)

XRN2 Lentiviral Activation Particles (h2)

sc-411608-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

XRN2 CRISPR Activation Plasmid (m)

sc-423994-ACTmGene ActivationPuro, Blast, Hygro0
(0)

XRN2 CRISPR Activation Plasmid (m2)

sc-423994-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

XRN2 Lentiviral Activation Particles (m)

sc-423994-LACmGene ActivationPuro, Blast, Hygro0
(0)

XRN2 Lentiviral Activation Particles (m2)

sc-423994-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

XRN siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

XRN1 siRNA (h)

sc-61811hGene SilencingN/A
2
(0)

XRN1 shRNA Plasmid (h)

sc-61811-SHhGene SilencingPuromycin
2
(0)

XRN1 shRNA (h) Lentiviral Particles

sc-61811-VhGene SilencingPuromycin
2
(0)

XRN1 siRNA (m)

sc-61812mGene SilencingN/A0
(0)

XRN1 shRNA Plasmid (m)

sc-61812-SHmGene SilencingPuromycin0
(0)

XRN1 shRNA (m) Lentiviral Particles

sc-61812-VmGene SilencingPuromycin0
(0)

XRN2 siRNA (h)

sc-61813hGene SilencingN/A
2
(0)

XRN2 shRNA Plasmid (h)

sc-61813-SHhGene SilencingPuromycin
2
(0)

XRN2 shRNA (h) Lentiviral Particles

sc-61813-VhGene SilencingPuromycin
2
(0)

XRN2 siRNA (m)

sc-61814mGene SilencingN/A0
(0)

XRN2 shRNA Plasmid (m)

sc-61814-SHmGene SilencingPuromycin0
(0)

XRN2 shRNA (m) Lentiviral Particles

sc-61814-VmGene SilencingPuromycin0
(0)