WDR47 Activators

Compounds such as Paclitaxel and Nocodazole, which modulate microtubule dynamics, can influence WDR47's role in microtubule organization and cellular transport. These agents could impact the way WDR47 interacts with microtubule structures, thereby affecting processes like intracellular trafficking and cell shape maintenance.

Actin dynamics are also crucial for WDR47's function, and compounds like Cytochalasin D, Latrunculin A, and Wiskostatin, by disrupting or stabilizing actin filaments, provide insights into WDR47's involvement in actin-mediated cellular processes. Inhibition of Cdc42 GTPase by ML141 and ROCK by Y-27632 further underscores the role of WDR47 in cytoskeletal regulation pathways. Furthermore, agents like Brefeldin A and Rapamycin, known for their roles in modulating intracellular transport and mTOR signaling pathways, respectively, might indirectly influence WDR47's functionality in these pathways. Compounds like Blebbistatin and Colchicine offer additional perspectives on WDR47's involvement in processes governed by myosin II activity and microtubule polymerization.