The chemical class termed WDR25 Activators encompasses a diverse group of molecules that can modulate various intracellular signaling pathways, which, in turn, intersect with the functional roles that WDR25 plays within the cell. These activators are characterized by their ability to engage with several cellular processes, ranging from gene expression regulation and signal transduction to proteostasis and apoptosis. They can exert their influence through the inhibition or activation of enzymes, modulation of receptor activities, or alteration of cellular metabolite levels. The broad spectrum of their actions is reflective of the multifaceted nature of cellular homeostasis and the complex interplay between different biochemical pathways.
The functional impact of WDR25 activators extends across several dimensions of cellular biology. For instance, some can engage with the machinery governing the cell cycle, thus affecting the proliferation and division of cells. Others can interact with the components responsible for cytoskeletal dynamics, influencing cell morphology and motility. Certain activators can also affect the ubiquitin-proteasome system, leading to changes in protein turnover, which is a critical aspect of cell regulation. Additionally, these compounds can influence chromatin remodeling and gene expression by modulating the activity of enzymes involved in epigenetic modifications. The consequences of these interactions are profound, as they can recalibrate cellular pathways and influence the functional state of WDR25. The efficacy and specificity of these activators are subject to cellular context and can vary according to the physiological state of the cell, the presence of other interacting proteins, and the broader cellular environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylyl cyclase, which increases cAMP levels and PKA activity, and these changes in signal transduction pathways could possibly activate WDR25. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor that induces DNA demethylation, which could possibly activate WDR25 by affecting gene expression and chromatin states it may regulate. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
GSK-3 inhibitor affecting Wnt signaling, which could possibly activate WDR25 through its cellular functions that intersect with this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor affecting cell growth and autophagy, processes that could possibly activate WDR25. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
TGF-β receptor inhibitor that modulates this signaling pathway and could possibly activate WDR25 by affecting its regulatory processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that could possibly activate WDR25 by changing MAPK/ERK signaling pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor that affects cytoskeletal organization and cell motility, which could possibly activate WDR25 if it is involved in these processes. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $75.00 | 256 | |
Pan-caspase inhibitor that inhibits apoptosis, which could possibly activate WDR25 by impacting cellular survival pathways it is connected to. | ||||||