Date published: 2026-5-30

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TUBAL3 Inhibitors

The chemical class referred to as TUBAL3 Inhibitors constitutes a group of compounds meticulously designed to selectively target the molecular entity TUBAL3. TUBAL3, or Tubulin Alpha Like 3, is a member of the tubulin superfamily, a group of proteins crucial for microtubule formation and dynamics within the cellular cytoskeleton. Microtubules are essential structural components involved in cellular processes such as cell division, intracellular transport, and maintenance of cell shape. While TUBAL3 shares homology with other tubulin isoforms, its distinct structural features and functions make it a subject of ongoing research within the fields of cell biology and molecular pharmacology. Inhibitors within the TUBAL3 Inhibitors class are intricately engineered molecules with the primary objective of modulating the activity or function of TUBAL3, thereby inducing an inhibitory effect. Researchers engaged in this field adopt a multifaceted approach, integrating insights from structural biology, medicinal chemistry, and computational modeling to unravel the complex molecular interactions between the inhibitors and the target TUBAL3.

Structurally, TUBAL3 Inhibitors are characterized by specific molecular features designed to facilitate selective binding to TUBAL3. This selectivity is essential to minimize unintended effects on other cellular components, ensuring a focused impact on the intended molecular target. The development of inhibitors within this chemical class involves a comprehensive exploration of structure-activity relationships, optimization of pharmacokinetic properties, and a deep understanding of the molecular mechanisms associated with TUBAL3. As researchers delve deeper into the functional aspects of TUBAL3 Inhibitors, the knowledge generated contributes not only to deciphering the specific roles of Tubulin Alpha Like 3 but also to advancing our broader comprehension of cellular dynamics, cytoskeletal organization, and the intricate processes governing cell division and intracellular transport. The exploration of TUBAL3 Inhibitors stands as a significant avenue for expanding fundamental knowledge in molecular biology and cellular physiology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

While paclitaxel is known to stabilize microtubules rather than inhibit their expression, it could indirectly influence TUBAL3 expression by disrupting microtubule dynamics.

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$100.00
$321.00
$2289.00
$4484.00
$18207.00
$34749.00
3
(2)

Colchicine binds to tubulin, inhibiting microtubule polymerization, which may alter the cell's regulatory mechanisms for tubulin expression, including TUBAL3.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

It disrupts microtubule networks by binding to beta-tubulin, and through feedback mechanisms, could affect the expression of tubulin genes.

Vinblastine

865-21-4sc-491749
sc-491749A
sc-491749B
sc-491749C
sc-491749D
10 mg
50 mg
100 mg
500 mg
1 g
$102.00
$235.00
$459.00
$1749.00
$2958.00
4
(0)

Vinblastine interferes with microtubule assembly. By disturbing microtubule dynamics, it may have an impact on TUBAL3 expression.

Podophyllotoxin

518-28-5sc-204853
100 mg
$84.00
1
(1)

It inhibits tubulin polymerization and, through complex feedback mechanisms, could potentially reduce TUBAL3 expression.

Griseofulvin

126-07-8sc-202171A
sc-202171
sc-202171B
5 mg
25 mg
100 mg
$85.00
$220.00
$598.00
4
(2)

Interferes with microtubule function and might affect the expression of tubulin genes through cellular stress responses.

Mebendazole

31431-39-7sc-204798
sc-204798A
5 g
25 g
$46.00
$89.00
2
(2)

Originally an antiparasitic, it can bind to tubulin and might influence TUBAL3 expression by affecting microtubule formation.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, it can change the expression of a wide range of genes, possibly including those encoding tubulins.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methyltransferase inhibitor can lead to DNA demethylation, which may affect the transcription of various genes, including possibly TUBAL3.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

It inhibits eukaryotic protein synthesis by interfering with the translocation step in protein synthesis, potentially reducing TUBAL3 levels.