Date published: 2025-10-25

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Thyroxine Inhibitors

Thyroxine inhibitors are a distinctive chemical class of compounds known for their specific ability to interact with and modulate the activity of thyroxine, a vital thyroid hormone. These inhibitors function by targeting the pathways involved in the synthesis, release, or uptake of thyroxine within the body. Through their intricate molecular interactions, thyroxine inhibitors can effectively hinder or regulate the production of thyroxine, leading to altered thyroid hormone levels.

These chemical agents play a crucial role in the intricate and finely balanced endocrine system, where even slight deviations in thyroid hormone levels can have significant effects on various physiological processes. As thyroxine is integral to the regulation of metabolism, growth, and development, thyroxine inhibitors hold significant scientific interest for researchers aiming to explore the complex mechanisms governing thyroid hormone regulation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Methimazole

60-56-0sc-205747
sc-205747A
10 g
25 g
$69.00
$110.00
4
(0)

Methimazole is an antithyroid agent in research that blocks the synthesis of thyroxine by interfering with the production of thyroid hormones in the thyroid gland.

Carbimazole

22232-54-8sc-205620
sc-205620A
1 g
5 g
$40.00
$130.00
(0)

Carbimazole (CAS 22232-54-8) is a chemical known for its role as an inhibitor of the Thyroxine protein. It acts by reducing the iodination of tyrosine residues in thyroglobulin, which in turn limits the synthesis of thyroid hormones. By interfering with the iodination process, Carbimazole decreases the availability of active Thyroxine, making it a valuable tool for research into thyroid function and hormone regulation.

6-Propyl-2-thiouracil

51-52-5sc-214383
sc-214383A
sc-214383B
sc-214383C
10 g
25 g
100 g
1 kg
$36.00
$55.00
$220.00
$1958.00
(0)

6-Propyl-2-thiouracil (CAS 51-52-5) is a sulfur-containing uracil derivative known for its function as an inhibitor of the Thyroxine protein. It acts by interfering with the iodination of tyrosine residues in thyroglobulin, a crucial step in Thyroxine synthesis. This compound is valuable in scientific research to study the mechanisms of thyroid hormone regulation and the biochemical pathways involved in hormone production and inhibition.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium has been shown to interfere with thyroid hormone release and can inhibit the action of thyroxine at the cellular level.

Amiodarone

1951-25-3sc-480089
5 g
$312.00
(1)

Amiodarone (CAS 1951-25-3) is a small molecule known for its role in inhibiting Thyroxine (T4) protein activity. It interferes with the binding of Thyroxine to its target proteins, reducing the downstream signaling events associated with the Thyroxine hormone. This inhibition is of interest in biochemical studies focusing on thyroid hormone regulation and its interactions with cellular targets. Amiodarone′s effect on Thyroxine provides valuable insights for researchers exploring hormone modulation mechanisms.

Aminoglutethimide

125-84-8sc-207280
sc-207280A
sc-207280B
sc-207280C
1 g
5 g
25 g
100 g
$41.00
$143.00
$530.00
$2020.00
2
(1)

Aminoglutethimide (CAS 125-84-8) functions as an inhibitor of the Thyroxine (T4) protein by interfering with the conversion of cholesterol into pregnenolone, a key step in steroid biosynthesis. This disruption leads to a reduction in the production of Thyroxine, affecting its overall activity in biological systems. Aminoglutethimide is used in scientific research to explore protein interactions and metabolic pathways related to Thyroxine regulation.