Date published: 2025-10-6

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SRD5A Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of SRD5A monoclonal antibodies for research in steroid metabolism. SRD5A monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SRD5A, or steroid 5-alpha-reductase, plays a crucial role in the conversion of testosterone to dihydrotestosterone (DHT), a potent androgen involved in various physiological processes. Understanding SRD5A function is essential for studying conditions such as androgenetic alopecia, benign prostatic hyperplasia, and certain forms of prostate cancer. The regulation of SRD5A activity has significant implications for hormonal therapies and drug development. Researchers worldwide rely on SRD5A monoclonal antibodies to advance their understanding of steroid metabolism pathways. Current investigations focus on how SRD5A influences hormone-dependent conditions and potential therapeutic interventions. SRD5A research continues to reveal new insights into endocrine system regulation and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers to make meaningful contributions to the advancement of steroid metabolism research and therapeutic development.

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SRD5A Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SRD5A2L2 Antibody (601CT22.4.3)

sc-517363mouse IgG1325-354 (h)WBh

new

(0)

SRD5A CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SRD5A2L CRISPR/Cas9 KO Plasmid (h)

sc-413197hGene KnockoutGFP0
(0)

SRD5A2L HDR Plasmid (h)

sc-413197-HDRhHomology Directed RepairPuromycin0
(0)

SRD5A2L Double Nickase Plasmid (h)

sc-413197-NIChGene KnockoutPuromycin0
(0)

SRD5A2L Double Nickase Plasmid (h2)

sc-413197-NIC-2hGene KnockoutPuromycin0
(0)

SRD5A3 CRISPR/Cas9 KO Plasmid (m)

sc-425391mGene KnockoutGFP0
(0)

SRD5A3 HDR Plasmid (m)

sc-425391-HDRmHomology Directed RepairPuromycin0
(0)

SRD5A3 Double Nickase Plasmid (m)

sc-425391-NICmGene KnockoutPuromycin0
(0)

SRD5A3 Double Nickase Plasmid (m2)

sc-425391-NIC-2mGene KnockoutPuromycin0
(0)

SRD5A2L2 CRISPR/Cas9 KO Plasmid (h)

sc-415179hGene KnockoutGFP0
(0)

SRD5A2L2 HDR Plasmid (h)

sc-415179-HDRhHomology Directed RepairPuromycin0
(0)

SRD5A2L2 Double Nickase Plasmid (h)

sc-415179-NIChGene KnockoutPuromycin0
(0)

SRD5A2L2 Double Nickase Plasmid (h2)

sc-415179-NIC-2hGene KnockoutPuromycin0
(0)

SRD5A2L2 CRISPR/Cas9 KO Plasmid (m)

sc-433952mGene KnockoutGFP0
(0)

SRD5A2L2 HDR Plasmid (m)

sc-433952-HDRmHomology Directed RepairPuromycin0
(0)

SRD5A2L2 Double Nickase Plasmid (m)

sc-433952-NICmGene KnockoutPuromycin0
(0)

SRD5A2L2 Double Nickase Plasmid (m2)

sc-433952-NIC-2mGene KnockoutPuromycin0
(0)

SRD5A CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SRD5A2L CRISPR Activation Plasmid (h)

sc-413197-ACThGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L CRISPR Activation Plasmid (h2)

sc-413197-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L Lentiviral Activation Particles (h)

sc-413197-LAChGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L Lentiviral Activation Particles (h2)

sc-413197-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SRD5A3 CRISPR Activation Plasmid (m)

sc-425391-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SRD5A3 CRISPR Activation Plasmid (m2)

sc-425391-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SRD5A3 Lentiviral Activation Particles (m)

sc-425391-LACmGene ActivationPuro, Blast, Hygro0
(0)

SRD5A3 Lentiviral Activation Particles (m2)

sc-425391-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 CRISPR Activation Plasmid (h)

sc-415179-ACThGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 CRISPR Activation Plasmid (h2)

sc-415179-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 Lentiviral Activation Particles (h)

sc-415179-LAChGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 Lentiviral Activation Particles (h2)

sc-415179-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 CRISPR Activation Plasmid (m)

sc-433952-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 CRISPR Activation Plasmid (m2)

sc-433952-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 Lentiviral Activation Particles (m)

sc-433952-LACmGene ActivationPuro, Blast, Hygro0
(0)

SRD5A2L2 Lentiviral Activation Particles (m2)

sc-433952-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SRD5A siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SRD5A2L siRNA (h)

sc-89215hGene SilencingN/A0
(0)

SRD5A2L shRNA Plasmid (h)

sc-89215-SHhGene SilencingPuromycin0
(0)

SRD5A2L shRNA (h) Lentiviral Particles

sc-89215-VhGene SilencingPuromycin0
(0)

SRD5A3 siRNA (m)

sc-153818mGene SilencingN/A0
(0)

SRD5A3 shRNA Plasmid (m)

sc-153818-SHmGene SilencingPuromycin0
(0)

SRD5A3 shRNA (m) Lentiviral Particles

sc-153818-VmGene SilencingPuromycin0
(0)

SRD5A2L2 siRNA (h)

sc-89196hGene SilencingN/A0
(0)

SRD5A2L2 shRNA Plasmid (h)

sc-89196-SHhGene SilencingPuromycin0
(0)

SRD5A2L2 shRNA (h) Lentiviral Particles

sc-89196-VhGene SilencingPuromycin0
(0)

SRD5A2L2 siRNA (m)

sc-153817mGene SilencingN/A0
(0)

SRD5A2L2 shRNA Plasmid (m)

sc-153817-SHmGene SilencingPuromycin0
(0)

SRD5A2L2 shRNA (m) Lentiviral Particles

sc-153817-VmGene SilencingPuromycin0
(0)