Date published: 2025-10-7

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Spin Traps, Spin Probes and Spin Labels

Santa Cruz Biotechnology now offers a broad range of Spin Traps, Spin Probes, and Spin Labels for use in various applications. Spin traps, spin probes, and spin labels are specialized chemicals used extensively in electron paramagnetic resonance (EPR) spectroscopy to detect, identify, and quantify free radicals and other paramagnetic species in various research contexts. Spin traps are compounds that react with transient free radicals to form more stable radical adducts, which can then be studied via EPR to provide insights into the dynamics and mechanisms of radical formation and decay. Spin probes are stable radicals that interact with their environment, allowing researchers to study the microenvironmental conditions, such as polarity and viscosity, within biological membranes or synthetic materials. Spin labels are specific molecules covalently attached to proteins, nucleic acids, or other macromolecules, facilitating the study of molecular structure, dynamics, and interactions through EPR. These tools are invaluable in fields such as biochemistry, molecular biology, and materials science, where understanding the behavior of free radicals and the structural properties of macromolecules is crucial. They enable the detailed study of oxidative stress, enzymatic activity, and the physical properties of polymers and other complex systems. By offering a diverse selection of high-quality spin traps, spin probes, and spin labels, Santa Cruz Biotechnology supports the scientific community in performing accurate and reproducible experiments, leading to new discoveries and advancements in various research areas. View detailed information on our available Spin Traps, Spin Probes, and Spin Labels by clicking on the product name.

Items 1 to 10 of 90 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MTSL

81213-52-7sc-208677
sc-208677A
10 mg
50 mg
$167.00
$653.00
56
(2)

MTSL is a versatile spin probe known for its unique ability to selectively interact with radical species, enabling precise detection and characterization of reactive intermediates. Its stable nitroxide structure allows for efficient electron spin resonance (ESR) studies, revealing insights into molecular dynamics and reaction mechanisms. The compound's distinctive electron distribution enhances its sensitivity to environmental changes, making it a powerful tool for investigating spin dynamics in complex systems.

DEPMPO

157230-67-6sc-202132
sc-202132A
50 mg
500 mg
$189.00
$1132.00
7
(1)

DEPMPO is a sophisticated spin trap that excels in capturing transient radical species, facilitating the study of reaction kinetics and mechanisms. Its unique structure promotes strong interactions with radicals, leading to stable adduct formation. This stability allows for detailed electron spin resonance (ESR) analysis, providing insights into molecular behavior and environmental influences. DEPMPO's distinct electronic properties enhance its effectiveness in probing dynamic systems, making it a valuable asset in radical research.

1-Oxyl-2,2,5,5-tetramethylpyrroline-3-carboxylate N-Hydroxysuccinimide Ester

37558-29-5sc-208680
10 mg
$238.00
(1)

1-Oxyl-2,2,5,5-tetramethylpyrroline-3-carboxylate N-Hydroxysuccinimide Ester serves as an advanced spin probe, adept at detecting and characterizing radical species through its unique electron-rich structure. Its ability to form stable spin adducts enables precise monitoring of radical dynamics and interactions. The compound's reactivity with various radicals allows for nuanced exploration of reaction pathways, enhancing the understanding of radical behavior in complex systems.

TOAC

15871-57-5sc-202366
100 mg
$99.00
(1)

TOAC is a versatile spin trap that excels in capturing transient radical species due to its unique electron-deficient nitrogen center. This compound facilitates the formation of stable radical adducts, allowing for detailed kinetic studies of radical reactions. Its distinctive steric and electronic properties enable selective interactions with specific radicals, providing insights into their mechanisms and lifetimes. The compound's robust stability under various conditions further enhances its utility in probing radical dynamics.

DMPO

3317-61-1sc-202587
sc-202587A
500 mg
1 g
$210.00
$312.00
6
(1)

DMPO is a prominent spin trap known for its ability to stabilize radical species through the formation of persistent adducts. Its unique structure allows for effective electron delocalization, which enhances the detection of short-lived radicals. The compound exhibits rapid reaction kinetics, making it ideal for real-time monitoring of radical processes. Additionally, DMPO's favorable solubility characteristics facilitate its use in diverse environments, enabling comprehensive studies of radical behavior and interactions.

4-Carboxy-TEMPO, free radical

37149-18-1sc-232531
250 mg
$136.00
2
(1)

4-Carboxy-TEMPO is a versatile spin probe that excels in detecting and characterizing radical species through its stable nitroxide structure. Its carboxyl group enhances solubility in polar solvents, promoting effective interactions with various radicals. The compound's unique electron paramagnetic resonance (EPR) properties allow for precise monitoring of radical dynamics and reaction pathways. Additionally, its ability to form stable adducts contributes to its utility in studying complex radical mechanisms and kinetics.

16-DOXYL-stearic acid, free radical

53034-38-1sc-251622
sc-251622A
10 mg
25 mg
$95.00
$210.00
2
(2)

16-DOXYL-stearic acid is a specialized spin probe that features a long hydrocarbon chain, enhancing its lipid solubility and enabling it to integrate into biological membranes. Its unique radical structure allows for sensitive detection of microenvironmental changes, making it effective in probing local dynamics and interactions. The compound's electron paramagnetic resonance (EPR) capabilities facilitate the exploration of spin relaxation processes and molecular mobility, providing insights into radical behavior in diverse environments.

rac-2,2,6,6-Tetramethylpiperidine-N-oxyl-4, 4-(5-spirohydantoin)

15871-56-4sc-212757
100 mg
$520.00
(0)

Rac-2,2,6,6-Tetramethylpiperidine-N-oxyl-4,4-(5-spirohydantoin) serves as a versatile spin trap and probe, characterized by its unique piperidine structure that enhances radical stability. Its distinctive spirohydantoin moiety facilitates selective interactions with reactive species, allowing for the capture and analysis of transient radicals. The compound's electron paramagnetic resonance (EPR) properties enable detailed studies of reaction kinetics and molecular dynamics, revealing insights into radical formation and decay pathways in complex systems.

Diethyldithiocarbamic acid sodium salt trihydrate

20624-25-3sc-202576
sc-202576A
5 g
25 g
$19.00
$58.00
2
(1)

Diethyldithiocarbamic acid sodium salt trihydrate functions as an effective spin trap and probe, distinguished by its dithiocarbamate structure that promotes strong interactions with free radicals. Its unique ability to form stable adducts with reactive species enhances the detection of transient radicals. The compound's solubility and reactivity facilitate detailed investigations into radical mechanisms, providing valuable insights into electron transfer processes and reaction kinetics in various environments.

3-(2-Iodoacetamido)-PROXYL

27048-01-7sc-209450
10 mg
$270.00
(0)

3-(2-Iodoacetamido)-PROXYL serves as a versatile spin probe, characterized by its nitroxide moiety that enables selective interactions with free radicals. This compound exhibits unique electron paramagnetic resonance (EPR) properties, allowing for real-time monitoring of radical dynamics. Its iodoacetamido group enhances reactivity, facilitating covalent bonding with target molecules. This specificity aids in elucidating complex biochemical pathways and understanding radical-mediated processes in diverse systems.