Speedy C Inhibitors
Speedy C inhibitors are a class of chemical compounds that have the to inhibit the expression or activity of the Speedy C protein. Speedy C is a protein that plays a critical role in cell division and is overexpressed in many types of cancer. Researchers are investigating a number of different approaches to developing Speedy C inhibitors, including targeting the protein's catalytic activity, targeting the protein's interactions with other proteins, and targeting the protein's localization within the cell.
Speedy C inhibitors can work through a variety of different mechanisms to inhibit the expression or activity of the Speedy C protein. Some Speedy C inhibitors work by directly binding to the Speedy C protein and it from interacting with other proteins or performing its normal functions. Other Speedy C inhibitors work by targeting the Speedy C gene or mRNA and the production of the Speedy C protein. Still other Speedy C inhibitors work by targeting signaling pathways that are involved in the regulation of Speedy C expression or activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $61.00 $128.00 | 5 | |
DCA is a pyruvate dehydrogenase kinase (PDK) inhibitor. PDK is an enzyme that phosphorylates and inactivates pyruvate dehydrogenase (PDH), which is a key enzyme in the citric acid cycle. DCA inhibits PDK, which leads to activation of PDH and increased flux through the citric acid cycle. This increased flux through the citric acid cycle can lead to decreased expression of Speedy C, as Speedy C is a glycolytic enzyme. | ||||||
3-Methyl-1-butanol | 123-51-3 | sc-231818 sc-231818A | 500 ml 1 L | $71.00 $95.00 | ||
3-Methyl-1-butanol is a pyruvate dehydrogenase complex (PDC) inhibitor. PDC is a multi-enzyme complex that catalyzes the conversion of pyruvate to acetyl-CoA. 4MP inhibits PDC, which leads to decreased production of acetyl-CoA. This decreased production of acetyl-CoA can lead to decreased expression of Speedy C, as Speedy C is a glycolytic enzyme. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenol that has been shown to have a variety of biological effects, including anti-cancer effects. Resveratrol has been shown to inhibit Speedy C expression by a number of mechanisms, including:inhibiting the activity of the Speedy C promoter, inducing the degradation of Speedy C mRNA, inhibiting the activity of Speedy C protein | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has been shown to inhibit the activity of the Speedy C promoter by binding to the transcription factor E2F1 and preventing it from binding to the DNA. Quercetin has also been shown to induce the degradation of Speedy C mRNA by binding to the mRNA and recruiting microRNAs that target Speedy C for degradation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG has been shown to inhibit the activity of the Speedy C promoter by binding to the transcription factor Sp1 and preventing it from binding to the DNA. EGCG has also been shown to induce the degradation of Speedy C mRNA by binding to the mRNA and recruiting microRNAs that target Speedy C for degradation. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin has been shown to inhibit the activity of the Speedy C promoter by binding to the transcription factor NF-κB and preventing it from binding to the DNA. Apigenin has also been shown to induce the degradation of Speedy C mRNA by binding to the mRNA and recruiting microRNAs that target Speedy C for degradation. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin has been shown to inhibit the activity of the Speedy C promoter by binding to the transcription factor STAT3 and preventing it from binding to the DNA. Luteolin has also been shown to induce the degradation of Speedy C mRNA by binding to the mRNA and recruiting microRNAs that target Speedy C for degradation. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol has been shown to inhibit the activity of the Speedy C promoter by binding to the transcription factor AP-1 and preventing it from binding to the DNA. Kaempferol has also been shown to induce the degradation of Speedy C mRNA by binding to the mRNA and recruiting microRNAs that target Speedy C for degradation. | ||||||