Date published: 2025-10-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

SIRT Inhibitors

Santa Cruz Biotechnology now offers a broad range of SIRT inhibitors for use in various applications. SIRT inhibitors, also known as sirtuin inhibitors, are compounds that inhibit the activity of sirtuinsenzymes that play crucial roles in cellular regulation, including aging, transcription, and apoptosis. In scientific research, SIRT inhibitors are invaluable for studying cellular processes and pathways, as they allow researchers to manipulate sirtuin activity and observe the resulting biological effects. These inhibitors are particularly important in understanding the regulation of metabolism, gene expression, and cell survival under stress conditions. By modulating sirtuin activity, scientists can explore the underlying mechanisms of age-related diseases and investigate the potential impacts of sirtuins on cellular longevity and healthspan. Additionally, SIRT inhibitors are used in biochemical assays to dissect the functions of different sirtuin isoforms, providing insights into their distinct and overlapping roles within cells. This makes them essential tools in molecular biology, biochemistry, and aging research. View detailed information on our available SIRT inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Aristoforin

849215-53-8sc-202958
1 mg
$151.00
1
(0)

Aristoforin acts as a sirtuin modulator, characterized by its ability to form stable complexes through π-π stacking and van der Waals interactions. Its unique structural features facilitate selective binding to sirtuin active sites, potentially influencing substrate recognition and catalytic efficiency. The compound's lipophilic nature enhances membrane permeability, allowing for efficient cellular uptake and interaction with intracellular targets, thereby affecting metabolic pathways.

Dihydrocoumarin

119-84-6sc-227867
sc-227867A
5 g
25 g
$17.00
$41.00
(0)

Dihydrocoumarin exhibits intriguing properties as a sirtuin modulator, primarily through its capacity to engage in hydrogen bonding and hydrophobic interactions. Its unique bicyclic structure allows for conformational flexibility, which may enhance its affinity for sirtuin enzymes. The compound's ability to stabilize enzyme-substrate complexes can influence enzymatic activity and regulatory mechanisms, potentially altering metabolic flux. Additionally, its moderate polarity aids in solubility, impacting bioavailability and interaction dynamics.