SERF2 Activators
SERF2 activators pertain to a class of chemical compounds that influence the activity of the small EDRK-rich factor 2 (SERF2) protein, which is involved in a range of cellular processes. SERF2 is a member of the small acidic protein family and has been implicated in the modulation of nucleic acid structures and the regulation of protein interactions. The specific mechanism by which SERF2 exerts its function is not entirely understood, but it is known to play a role in the complex orchestration of cellular homeostasis. Activators of SERF2 can bind or interact with the protein, leading to an increase in its activity. This can result in alterations to the dynamics of nucleic acid conformation and influence the assembly of protein complexes, thereby impacting various intracellular signaling pathways and cellular functions.
The chemistry of SERF2 activators is diverse, with molecules varying in structure and size, reflecting the different methods by which they can enhance SERF2 activity. These compounds may interact with SERF2 directly, binding to allosteric sites that induce a conformational change that increases its activity, or they may interact indirectly, by affecting the expression levels of SERF2 or the stability of the protein, leading to an increased concentration within the cell. The molecular design of SERF2 activators often incorporates functional groups that are capable of engaging in specific interactions with amino acid residues of the protein, facilitating a higher affinity and selectivity for SERF2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, leading to an increase in cAMP levels. Elevated cAMP activates PKA, which can phosphorylate substrates involved in neuroprotective pathways, potentially enhancing the neuroprotective role of SERF2. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits phosphodiesterase 4 (PDE4), preventing cAMP degradation. This elevation in cAMP levels can result in increased PKA activity, potentially enhancing the neuroprotective function of SERF2 through phosphorylation of related substrates. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits multiple kinases, leading to altered signaling pathways that could indirectly enhance the neuroprotective effects of SERF2 by reducing competitive signaling. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, a protein deacetylase, which is involved in stress response pathways. Activation of SIRT1 can lead to deacetylation of proteins that could be involved in the same pathways as SERF2, indirectly enhancing its functional activity. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine induces autophagy through inhibition of acetyltransferase, which can lead to the degradation of damaged proteins and organelles. This process might indirectly enhance the role of SERF2 in cellular stress responses. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid modulates gene expression through retinoic acid receptors. This modulation can lead to changes in cell differentiation pathways that involve SERF2, potentially enhancing its activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates several signaling pathways including NF-κB, which could lead to an indirect enhancement of the functional activity of SERF2 in stress response pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium inhibits glycogen synthase kinase-3 (GSK-3), which may lead to the stabilization and activation of proteins involved in neuroprotective pathways, potentially enhancing the functional activity of SERF2. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium butyrate acts as a histone deacetylase inhibitor, leading to changes in chromatin structure and gene expression. These changes might enhance the functional activity of SERF2 through epigenetic regulation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc serves as a cofactor for many enzymes and is involved in numerous cellular processes, including those that may activate or enhance the function of SERF2 through interactions with proteins and signaling pathways. | ||||||