Sectm1a inhibitors are a class of chemical compounds that specifically target and inhibit the function of the protein Sectm1a (Secreted and transmembrane 1A). Sectm1a is a type I transmembrane protein that plays a role in various cellular processes, including immune cell interactions and cellular signaling pathways. The inhibition of Sectm1a can be achieved through small molecules, peptides, or monoclonal antibodies that bind to specific regions of the protein, preventing its interaction with ligands or other cellular components. These inhibitors are designed to disrupt the function of Sectm1a by altering its conformational state or blocking its interaction domains, thereby hindering its biological activity within the cellular environment.
Structurally, Sectm1a inhibitors are diverse, with different chemical scaffolds being employed depending on the specific target site within the protein. These inhibitors can be categorized based on their binding affinity, specificity, and mechanism of action, such as competitive inhibition or allosteric modulation. Some Sectm1a inhibitors may act by binding to the active site of the protein, while others may induce conformational changes that destabilize its functional structure. Researchers studying Sectm1a inhibitors typically focus on understanding their physicochemical properties, including molecular weight, solubility, and stability, to optimize their function in vitro. Advanced computational modeling techniques are often employed to predict the binding interactions between Sectm1a and its inhibitors, aiding in the rational design and synthesis of more effective compounds.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An immunosuppressant that inhibits calcineurin, potentially affecting T cell activation and cytokine production. Cyclosporine A could indirectly influence Sectm1a by altering T cell responses and immune signaling pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, a key regulator of cell growth and immune responses. Rapamycin could indirectly impact Sectm1a activity through its effects on T cell and NK cell function. | ||||||
Azathioprine | 446-86-6 | sc-210853D sc-210853 sc-210853A sc-210853B sc-210853C | 500 mg 1 g 2 g 5 g 10 g | $203.00 $176.00 $349.00 $505.00 $704.00 | 1 | |
An immunosuppressive drug that inhibits purine synthesis, potentially affecting lymphocyte proliferation and function. Azathioprine could indirectly influence Sectm1a activity by modulating immune cell responses. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $42.00 $136.00 $676.00 | 2 | |
A corticosteroid used as an anti-inflammatory and immunosuppressant. Prednisone could indirectly affect Sectm1a by altering immune responses and inflammation. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
An antimetabolite and immunosuppressant used in various autoimmune diseases. Methotrexate could indirectly influence Sectm1a activity by affecting lymphocyte function and immune regulation. | ||||||
Mycophenolate mofetil | 128794-94-5 | sc-200971 sc-200971A | 20 mg 100 mg | $37.00 $109.00 | 1 | |
Inhibits inosine monophosphate dehydrogenase, affecting lymphocyte proliferation. Mycophenolate Mofetil could indirectly influence Sectm1a by altering immune cell activities. | ||||||