RPS4YX Activators
The protein RPS4YX, ribosomal protein S4 Y-linked, is a key constituent of the small ribosomal subunit (40S) involved in mRNA decoding during translation, thus playing a fundamental role in protein synthesis. Beyond its canonical function in ribosome biogenesis, RPS4YX is implicated in various cellular processes such as cell growth, proliferation, and differentiation. Although predominantly expressed in testicular tissues, suggesting potential roles in spermatogenesis, the precise functions of RPS4YX in other tissues remain to be fully elucidated. Nevertheless, its involvement in protein synthesis underscores its significance in cellular homeostasis and function.
Activation of RPS4YX entails intricate regulatory mechanisms that govern its expression and activity. Various signaling pathways and transcriptional factors are implicated in modulating RPS4YX expression levels. Additionally, post-translational modifications such as phosphorylation or acetylation may influence its activity, impacting ribosome biogenesis and protein synthesis. Furthermore, upstream regulators of RPS4YX, including growth factors or hormones, can activate signaling cascades that ultimately enhance its function. Understanding the precise mechanisms of RPS4YX activation is crucial for deciphering its physiological roles and may offer insights into manipulating protein synthesis in diverse biological contexts.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP levels by activating adenylate cyclase. Elevated cAMP activates PKA, which in turn can phosphorylate proteins that might interact with or modify RPS4YX, leading to its enhanced functional activity. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits phosphodiesterase-4, thus preventing cAMP degradation. The resulting increase in cAMP levels can indirectly enhance RPS4YX activity through PKA-mediated signaling pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, leading to increased cAMP and cGMP levels in cells. This can indirectly enhance RPS4YX activity by influencing PKA and PKG pathways. | ||||||
Cilostamide (OPC 3689) | 68550-75-4 | sc-201180 sc-201180A | 5 mg 25 mg | $92.00 $357.00 | 16 | |
Cilostamide selectively inhibits phosphodiesterase-3, increasing cAMP levels. Higher cAMP can activate PKA, which may positively influence RPS4YX activity through phosphorylation of associated proteins. | ||||||
Vinpocetine | 42971-09-5 | sc-201204 sc-201204A sc-201204B | 20 mg 100 mg 15 g | $55.00 $214.00 $2400.00 | 4 | |
Vinpocetine inhibits phosphodiesterase-1, leading to increased cAMP and cGMP levels. This can indirectly activate RPS4YX through PKA and PKG dependent pathways that can modify proteins interacting with RPS4YX. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $105.00 $250.00 | 8 | |
Zaprinast selectively inhibits phosphodiesterase-5, which increases cGMP levels. Elevated cGMP can enhance RPS4YX activity by activating PKG-dependent signaling pathways. | ||||||
Anagrelide | 68475-42-3 | sc-491875 | 25 mg | $150.00 | ||
Anagrelide inhibits phosphodiesterase-3, leading to increased cAMP levels and activation of PKA. This, in turn, can enhance the activity of RPS4YX via phosphorylation of proteins in the associated signaling cascade. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $165.00 $697.00 | 7 | |
Milrinone selectively inhibits phosphodiesterase-3, increasing intracellular cAMP levels. This elevation of cAMP can indirectly enhance RPS4YX activity through PKA-mediated phosphorylation mechanisms. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin is a PDE inhibitor known to increase cAMP levels, which can enhance RPS4YX activity through PKA-mediated pathways and potential phosphorylation of associated proteins. | ||||||
Dipyridamole | 58-32-2 | sc-200717 sc-200717A | 1 g 5 g | $31.00 $102.00 | 1 | |
Dipyridamole inhibits phosphodiesterase and can increase cAMP levels. This elevation can subsequently enhance RPS4YX activity via PKA-dependent signaling pathways. | ||||||