RIMBP3C, or RIM Binding Protein 3C, is part of the RIMBP family, which are proteins known to interact with RIM (Rab3-interacting molecule) proteins at active zones of synapses. RIM proteins are critical for synaptic vesicle release and are involved in the organization of the presynaptic machinery. Although RIMBP3C is not as extensively studied as other synaptic proteins, it is believed to play a role in the intricate network of protein-protein interactions that orchestrate neurotransmitter release.
The RIMBP family members are characterized by their ability to bind to RIM proteins, and they are thought to contribute to the stabilization of RIM at the active zone and to the overall structural integrity of the synaptic apparatus. RIMBP3C, by association, may influence synaptic plasticity and transmission. It is likely involved in the molecular events that underlie the precise release of neurotransmitters, which is essential for effective neural communication.RIMBP proteins have been implicated in the clustering of voltage-gated calcium channels at the presynaptic terminal, a process essential for the initiation of synaptic vesicle exocytosis upon membrane depolarization. Hence, RIMBP3C might play a supportive role in the localization or function of these channels, thereby indirectly modulating synaptic activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, leading to increased cAMP levels, which may influence RIMBP3C indirectly by modulating cAMP-dependent pathways. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
A cAMP analog that can affect signaling pathways related to RIMBP3C by bypassing the activation of adenylyl cyclase. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-specific inhibitor of phosphodiesterases, IBMX raises intracellular cAMP levels, potentially modulating RIMBP3C activity indirectly. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 interacts with its receptors to modulate adenylate cyclase activity, potentially influencing RIMBP3C through cAMP-dependent mechanisms. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
As a selective phosphodiesterase 4 inhibitor, Rolipram increases cAMP levels, which could indirectly affect RIMBP3C. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A synthetic analog of cAMP, potentially influencing RIMBP3C by modulating cAMP-dependent signaling. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine can modulate adenylate cyclase activity through its receptors, potentially influencing RIMBP3C via cAMP pathways. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Influences adrenergic receptors, affecting adenylate cyclase and cAMP levels, which may indirectly affect RIMBP3C. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $31.00 $145.00 | 16 | |
Activates adenylate cyclase via its receptor, potentially influencing RIMBP3C through cAMP-mediated pathways. | ||||||