QM inhibitors are a class of chemical compounds that have attracted attention in the fields of molecular biology due to modulate specific cellular processes. The term "QM" typically refers to quinone methide, which is a reactive intermediate in various biochemical reactions. Quinone methides can be involved in diverse biological processes, including oxidative stress responses and the activation of cellular signaling pathways. QM inhibitors are designed to interact with the active sites or binding domains of quinone methides or related molecules, effectively inhibiting their function and influencing cellular processes dependent on QM-mediated reactions.
Structurally, QM inhibitors are engineered to selectively target quinone methides or related intermediates, ensuring high specificity for these particular reactive species. By inhibiting the formation or reactivity of quinone methides, these compounds may disrupt their roles in cellular processes, impacting oxidative stress responses, redox signaling, or other biochemical pathways involving QM intermediates. The study of QM inhibitors is of significant interest to researchers as it provides insights into the regulatory mechanisms governing essential cellular functions related to reactive intermediates and their involvement in various signaling cascades. This knowledge contributes to our understanding of basic cell biology and may have implications in diverse research areas, including oxidative stress biology, cell signaling, and the molecular basis of diseases associated with dysregulated redox processes. However, further research is required to fully explore the extent of their applications and their impact on cellular physiology in the context of QM-mediated reactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Known to inhibit bacterial protein synthesis; in eukaryotes, it might affect mitochondrial ribosomes, potentially impacting QM expression. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $352.00 $566.00 $1331.00 $2453.00 | ||
Inhibits eukaryotic protein synthesis at the level of translation, which could reduce QM expression. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $51.00 $123.00 $178.00 | 11 | |
Inhibits protein synthesis by preventing the initial elongation step of translation, potentially affecting QM expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Blocks eukaryotic translational elongation, which could indirectly decrease QM protein levels. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Causes premature chain termination during protein synthesis; might indirectly reduce QM expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II, potentially reducing mRNA synthesis including QM mRNA. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and inhibits transcription, potentially decreasing QM expression. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits peptide bond formation in protein synthesis, potentially affecting QM expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Inhibits N-linked glycosylation, impacting protein folding and potentially QM expression. | ||||||
Diphtheria Toxin, CRM Mutant | 92092-36-9 | sc-203924 | 0.25 mg | $639.00 | 1 | |
Inhibits protein synthesis by ADP-ribosylating elongation factor 2, potentially impacting QM expression. | ||||||