Date published: 2025-10-18

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Photoreactive Crosslinkers

Santa Cruz Biotechnology now offers a broad range of photoreactive crosslinkers for use in various applications. Photoreactive crosslinkers are versatile compounds used to study the spatial and temporal interactions between biomolecules. These crosslinkers contain photoactivatable groups that, upon exposure to UV light, form covalent bonds with nearby molecules. This property makes them invaluable for capturing transient and weak interactions that are otherwise difficult to study. Researchers use photoreactive crosslinkers to map protein-protein, protein-DNA, and protein-RNA interactions, providing detailed insights into the complex networks that regulate cellular functions. These crosslinkers are also employed in structural biology to stabilize protein complexes for analysis by techniques such as X-ray crystallography and cryo-electron microscopy. Additionally, photoreactive crosslinkers are used in the development of biomaterials, where they facilitate the creation of stable and functionalized surfaces. By offering a comprehensive selection of high-quality photoreactive crosslinkers, Santa Cruz Biotechnology supports advanced research in biochemistry, molecular biology, and materials science. These products enable scientists to perform precise and reproducible experiments, driving innovations in understanding molecular interactions and developing new technologies. View detailed information on our available photoreactive crosslinkers by clicking on the product name.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SASD

144650-95-3sc-220093
10 mg
$330.00
(0)

SASD is a photoreactive crosslinker distinguished by its unique reactivity profile, featuring a highly reactive carbonyl group that engages in selective nucleophilic addition. Upon exposure to light, it initiates rapid crosslinking through a series of well-defined reaction pathways, leading to robust covalent networks. Its structural attributes promote favorable kinetics, allowing for fine-tuned manipulation of polymer properties, while its inherent stability under various conditions enhances its utility in complex systems.