Date published: 2025-10-14

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pH Indicators

Santa Cruz Biotechnology now offers a broad range of pH Indicators for use in various applications. pH indicators are vital chemical compounds that change color in response to changes in pH, providing a visual representation of the acidity or alkalinity of a solution. In scientific research, these indicators are crucial for experiments requiring precise pH conditions, enabling researchers to maintain and verify the pH of environments in biochemical and chemical reactions. The utility of pH indicators extends across disciplines, including chemistry, environmental science, and molecular biology, where they serve as essential tools for monitoring reactions, studying enzyme activities, and investigating metabolic pathways. The ability to quickly assess pH values with indicators aids in the optimization of conditions for experimental protocols and ensures the reproducibility of results. These indicators are especially important in studies involving biochemical systems where pH can influence the activity and stability of molecules like proteins and nucleic acids. Advances in pH indicator technology have led to the development of more sensitive and selective indicators that can provide real-time, quantifiable data essential for detailed scientific analysis. The diversity of available pH indicators, each with unique transition pH ranges and colors, allows for their application in a variety of experimental scenarios, supporting a broad range of scientific inquiries. These compounds are integral to the toolkit of researchers aiming to explore and manipulate the chemical foundations of biological processes. View detailed information on our available pH Indicators by clicking on the product name.

Items 31 to 40 of 54 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chlorophenol Red

4430-20-0sc-206022
10 g
$112.00
(0)

Chlorophenol Red is a pH indicator that undergoes a notable color change in response to varying acidity levels, transitioning from yellow to red. This behavior is attributed to its unique molecular structure, which allows for protonation and deprotonation processes that alter its electronic configuration. The compound exhibits strong intermolecular interactions, including hydrogen bonding, which influence its solubility and reactivity in different pH environments, making it a fascinating subject for studies in acid-base chemistry.

Resorufin sodium salt

34994-50-8sc-206019
sc-206019A
sc-206019B
500 mg
1 g
5 g
$245.00
$367.00
$1403.00
5
(0)

Resorufin sodium salt is a fluorescent compound that exhibits distinct colorimetric changes in response to pH variations, shifting from a non-fluorescent to a highly fluorescent state. This transformation is driven by its unique electron-rich structure, which facilitates protonation and deprotonation. The compound's ability to form stable complexes with metal ions enhances its reactivity, while its solubility in aqueous environments allows for dynamic interactions in diverse chemical settings.

1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt

59572-10-0sc-208786
1 g
$94.00
(1)

1,3,6,8-Pyrenetetrasulfonic acid tetrasodium salt is a highly soluble fluorescent dye characterized by its strong anionic nature, which influences its interactions with cations and other charged species. Its unique pyrene core allows for effective π-π stacking and excimer formation, leading to distinct photophysical properties. The compound's sulfonate groups enhance solubility in polar solvents, facilitating its role in various electrochemical and spectroscopic applications.

5-Carboxyfluorescein

76823-03-5sc-205903
sc-205903A
100 mg
250 mg
$129.00
$275.00
1
(1)

5-Carboxyfluorescein is a versatile fluorescent compound notable for its pH-sensitive properties, which enable it to exhibit distinct fluorescence changes in response to varying acidity levels. The carboxyl group facilitates hydrogen bonding and ionic interactions, enhancing its solubility in aqueous environments. Its unique structure allows for efficient energy transfer and photostability, making it an effective probe for studying dynamic biological processes and environmental conditions.

5(6)-Carboxy-2′,7′-dichlorofluorescein

111843-78-8sc-210420
100 mg
$110.00
(0)

5(6)-Carboxy-2',7'-dichlorofluorescein is a highly sensitive fluorescent indicator that responds to pH changes through a reversible protonation mechanism. The presence of dichloro substituents enhances its electronic properties, leading to pronounced shifts in fluorescence intensity across different pH levels. This compound's unique structural features promote strong interactions with surrounding molecules, allowing for precise monitoring of acidic and basic environments in various experimental setups.

Chlorophenol Red sodium salt

123333-64-2sc-214683
10 g
$114.00
(0)

Chlorophenol Red sodium salt is a pH indicator characterized by its distinct colorimetric response to acidity and alkalinity. Its molecular structure features a phenolic group that undergoes protonation and deprotonation, resulting in a vivid color change. The compound exhibits strong intermolecular interactions, particularly hydrogen bonding, which influences its reaction kinetics. This behavior allows for effective visualization of pH transitions, making it a reliable tool for monitoring environmental conditions.

6-Carboxy-fluorescein diacetate N-succinimidyl ester

150206-15-8sc-217319
5 mg
$124.00
(0)

6-Carboxy-fluorescein diacetate N-succinimidyl ester is a fluorescent probe that exhibits pH-dependent behavior through its unique molecular structure. The compound's carboxyl groups can engage in protonation, altering its fluorescence intensity in response to pH changes. This dynamic interaction enhances its sensitivity to environmental shifts, while the ester moieties facilitate cellular uptake and subsequent hydrolysis, leading to distinct fluorescence characteristics that are influenced by local pH conditions.

α-Naphtholbenzein

145-50-6sc-214451
sc-214451A
5 g
25 g
$38.00
$135.00
(0)

α-Naphtholbenzein is a pH indicator characterized by its distinct colorimetric response to acidity and alkalinity. Its molecular structure allows for reversible protonation, which alters the electronic distribution and leads to significant changes in absorbance. This compound exhibits a unique dual-state behavior, transitioning between a neutral and anionic form, which influences its spectral properties. The kinetics of these transitions are rapid, making it a sensitive marker for pH fluctuations in various environments.

Thiazole yellow G

1829-00-1sc-215968
sc-215968A
5 g
25 g
$20.00
$45.00
(0)

Thiazole yellow G is a pH-sensitive dye known for its vibrant color changes in response to varying acidity levels. Its unique structure facilitates intramolecular charge transfer, resulting in distinct optical properties. The compound undergoes protonation and deprotonation, which significantly alters its electronic configuration and absorption spectrum. This dynamic behavior allows for quick response times, making it an effective indicator for monitoring pH shifts in diverse conditions.

o-Cresolphthalexon

2411-89-4sc-215602
sc-215602A
1 g
5 g
$32.00
$101.00
(0)

o-Cresolphthalexon is a versatile pH indicator characterized by its ability to form stable complexes with metal ions, enhancing its sensitivity to pH changes. Its unique molecular structure allows for significant alterations in color due to protonation events, which influence its electronic transitions. The compound exhibits rapid reaction kinetics, making it suitable for real-time pH monitoring. Its distinct chromatic shifts are attributed to the interplay of resonance and steric effects within its aromatic framework.