PEG Linkers

3,4-Dibromo-Mal-PEG2-amine is a versatile PEG linker characterized by its unique dibromo substituents, which enhance its reactivity towards nucleophiles. This compound facilitates rapid and selective conjugation with various functional groups, promoting efficient molecular assembly. The malonate structure provides a reactive site for further modifications, while the PEG chain contributes to improved solubility and biocompatibility, making it suitable for diverse applications in chemical synthesis.

Biotin-PEG7-azide is a specialized PEG linker distinguished by its azide functionality, which enables click chemistry reactions, particularly with alkynes. This compound exhibits high stability under physiological conditions, allowing for controlled conjugation processes. The biotin moiety enhances binding affinity to streptavidin, facilitating targeted interactions. Its hydrophilic PEG chain improves solubility and reduces non-specific binding, making it ideal for precise molecular engineering and assembly.

Biotin-PEG23-azide is a versatile PEG linker characterized by its elongated hydrophilic chain and azide group, which promotes efficient click chemistry with terminal alkynes. The extended PEG segment enhances solubility and biocompatibility, while the biotin component ensures strong affinity for streptavidin, enabling selective targeting. This compound's unique structure allows for rapid reaction kinetics and minimal steric hindrance, making it suitable for advanced bioconjugation applications.

Diazo biotin-PEG3-szide is a specialized PEG linker featuring a diazo group that facilitates unique reactivity in bioconjugation processes. Its hydrophilic PEG chain enhances solubility, while the diazo moiety allows for selective and efficient coupling reactions. This compound exhibits rapid reaction kinetics, enabling precise modifications in complex biological systems. The combination of its structural elements promotes minimal steric hindrance, optimizing interactions with various biomolecules.

Biotin-PEG3-hydrazide is a versatile PEG linker characterized by its hydrazide functional group, which enables specific conjugation to carbonyl-containing molecules. The hydrophilic PEG segment enhances solubility and biocompatibility, while the hydrazide moiety allows for stable formation of hydrazone bonds, facilitating targeted modifications. This compound demonstrates favorable reaction kinetics, promoting efficient coupling in diverse biochemical environments, and minimizes steric hindrance, ensuring effective interactions with proteins and other biomolecules.

Biotin-PEG3-NHS ester is a specialized PEG linker featuring an N-hydroxysuccinimide (NHS) group, which facilitates rapid and efficient conjugation to amine-containing substrates. The hydrophilic PEG chain enhances solubility and reduces non-specific binding, while the NHS moiety promotes stable amide bond formation. This compound exhibits excellent reaction kinetics, allowing for precise modifications in various biochemical contexts, and its structure minimizes steric hindrance, optimizing interactions with target molecules.

Sulfo-Cy5.5 azide is a versatile PEG linker characterized by its azide functional group, enabling click chemistry reactions with alkyne-containing partners. This compound exhibits high water solubility due to its PEG backbone, which enhances biocompatibility and reduces aggregation. The azide group allows for selective and efficient labeling, facilitating precise modifications in complex biological systems. Its unique reactivity and stability make it ideal for creating robust conjugates in diverse applications.

Cy5.5 DBCO is a specialized PEG linker featuring a DBCO (dibenzocyclooctyne) moiety, known for its rapid and selective reaction with azides through strain-promoted alkyne-azide cycloaddition. This compound boasts excellent solubility in aqueous environments, attributed to its PEG structure, which minimizes non-specific interactions. Its unique reactivity profile allows for efficient conjugation, making it suitable for intricate labeling and tracking in various experimental contexts.

Cyanine 5.5 phosphoramidite serves as a versatile PEG linker, characterized by its robust photostability and high quantum yield. This compound facilitates efficient nucleophilic substitution reactions, enhancing the formation of stable conjugates. Its hydrophilic nature, derived from the PEG component, promotes solubility in biological systems, reducing aggregation. The unique electronic properties of the cyanine dye enable effective energy transfer, making it ideal for applications requiring precise signal detection.

Disulfo-cyanide 7 azide functions as a specialized PEG linker, notable for its unique reactivity and ability to form stable covalent bonds through azide-alkyne cycloaddition. This compound exhibits a high degree of selectivity in cross-linking reactions, allowing for tailored molecular architectures. Its dual sulfonyl groups enhance solubility and facilitate interactions with various biomolecules, while its azide functionality enables versatile labeling and functionalization strategies.