PECI Inhibitors
PECI inhibitors are chemicals that modulate the activity of the Peroxisomal Enoyl-CoA Hydratase-1 (PECI) enzyme, which plays a crucial role in lipid metabolism. PECI catalyzes the hydration of enoyl-CoA intermediates during the degradation of fatty acids within peroxisomes. By inhibiting PECI, these compounds interfere with this enzymatic conversion, potentially leading to a downstream impact on lipid processing and metabolic pathways.
PECI inhibitors bind to the active site of the enzyme, disrupting its normal function. This class of inhibitors represents a significant advancement in the field of cellular and molecular research, offering a tool to elucidate the intricacies of lipid metabolism and its broader implications for cellular health.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
GSK690693 is a kinase inhibitor that has also been shown to inhibit PECI. It was initially developed for cancer therapy but has been explored for its effects on fatty acid metabolism and insulin sensitivity. | ||||||
ESI-09 | 263707-16-0 | sc-507491 | 5 mg | $230.00 | ||
ESI-09 is a selective inhibitor of PECI that has been used in research to study the enzyme's role in fatty acid metabolism and cellular processes. | ||||||
Mevastatin (Compactin) | 73573-88-3 | sc-200853 sc-200853A | 10 mg 50 mg | $77.00 $179.00 | 18 | |
ML-236B is a natural compound that has been investigated for its inhibitory effects on PECI as well as other enzymes involved in lipid metabolism. It has been studied in the context of cholesterol synthesis. | ||||||