PANK3 Activators
PANK3, short for Pantothenate Kinase 3, is a protein that in humans is encoded by the PANK3 gene. This protein is a member of the pantothenate kinase family, which are key regulatory enzymes in the biosynthesis of Coenzyme A (CoA), a vital molecule involved in numerous cellular processes, including energy metabolism and the synthesis and degradation of fatty acids.The PANK3 protein catalyzes the first step in CoA biosynthesis, which is the phosphorylation of pantothenate (vitamin B5) to form 4'-phosphopantothenate. This step is crucial in controlling the rate of CoA synthesis.
PANK3 is one of four pantothenate kinases in humans (PANK1, PANK2, PANK3, and PANK4) and is known for its unique tissue-specific expression. While the other PANK enzymes are widely distributed in different tissues, PANK3 expression is primarily restricted to the testes.Despite this specific expression, the exact role and significance of PANK3 in testicular function and overall human physiology are not well understood. The functions of PANK1 and PANK2 have been more extensively studied, and mutations in the PANK2 gene are known to cause a rare neurodegenerative disease called Pantothenate Kinase-Associated Neurodegeneration (PKAN).
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cysteamine | 60-23-1 | sc-217991 sc-217991A sc-217991B | 5 g 25 g 50 g | $89.00 $238.00 $442.00 | 1 | |
A molecule that can affect CoA levels and might indirectly influence PANK3 activity. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
An antioxidant that might indirectly affect PANK3 by altering cellular redox states. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
An antioxidant involved in mitochondrial function, potentially influencing PANK3's metabolic context. | ||||||
Coenzyme A | 85-61-0 anhydrous | sc-211123 sc-211123A sc-211123B sc-211123C | 10 mg 25 mg 100 mg 250 mg | $83.00 $135.00 $418.00 $801.00 | 1 | |
Directly involved in PANK3's metabolic pathway, could impact its regulation through feedback mechanisms. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
An AMPK activator, which might influence PANK3 activity through energy balance and metabolic regulation. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
An AMPK activator commonly used in diabetes, potentially affecting PANK3's metabolic role. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
A NAD+ precursor, which could influence PANK3 activity through NAD+/NADH balance and metabolism. | ||||||
Riboflavin | 83-88-5 | sc-205906 sc-205906A sc-205906B | 25 g 100 g 1 kg | $41.00 $112.00 $525.00 | 3 | |
Involved in redox reactions, might indirectly influence PANK3 through cellular redox states. | ||||||