Orexin R-2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TCS OX2 29 | 372523-75-6 | sc-204329 sc-204329A | 10 mg 50 mg | $185.00 $781.00 | ||
TCS OX2 29 functions as a selective agonist for the orexin receptor 2, showcasing a unique ability to stabilize receptor conformations that promote activation. Its intricate molecular design facilitates specific hydrophobic interactions, enhancing receptor affinity and triggering distinct intracellular signaling pathways. The compound's kinetic profile indicates rapid receptor engagement, while its lipophilic nature supports efficient membrane permeability, optimizing its interaction dynamics within cellular environments. | ||||||
TCS 1102 | 916141-36-1 | sc-361375 sc-361375A | 10 mg 50 mg | $153.00 $643.00 | ||
TCS 1102 acts as a selective antagonist for the orexin receptor 2, exhibiting a unique capacity to disrupt receptor-ligand interactions. Its structural characteristics allow for specific electrostatic interactions that hinder receptor activation, effectively modulating downstream signaling pathways. The compound's kinetic behavior reveals a slow dissociation rate from the receptor, contributing to prolonged effects. Additionally, its polar nature influences solubility and distribution within biological systems, impacting its overall interaction profile. | ||||||
EMPA | 680590-49-2 | sc-498747 | 10 mg | $380.00 | ||
Dual orexin receptor antagonist with preference for Orexin R-2. EMPA modulates orexin signaling, influencing the activity of Orexin R-2 and disrupting downstream cellular responses. | ||||||
SB-334867 | 792173-99-0 | sc-507323 | 10 mg | $207.00 | ||
Selective antagonist of Orexin R-1 and R-2, specifically inhibiting orexin-induced responses. SB-334867 interferes with the binding of orexin to Orexin R-2, blocking receptor activation and subsequent cellular effects. | ||||||
Almorexant | 871224-64-5 | sc-507322 | 10 mg | $330.00 | ||
Dual orexin receptor antagonist, with affinity for both Orexin R-1 and R-2. Almorexant modulates orexin signaling pathways, influencing the activity of Orexin R-2 and interrupting downstream cellular responses mediated by orexin receptors. | ||||||
JNJ 10397049 | 708275-58-5 | sc-491320 | 1 mg | $189.00 | 1 | |
Potent and selective antagonist of Orexin R-2, inhibiting orexin-induced responses. JNJ-10397049 competitively binds to Orexin R-2, preventing receptor activation and downstream signal transduction. | ||||||
Filorexant | 1088991-73-4 | sc-507325 | 10 mg | $380.00 | ||
Dual orexin receptor antagonist with affinity for Orexin R-2. Filorexant modulates orexin signaling pathways, influencing the activity of Orexin R-2 and disrupting downstream cellular responses mediated by orexin receptors. | ||||||