OR13C4 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Icilin | 36945-98-9 | sc-201557 sc-201557A | 10 mg 50 mg | $89.00 $252.00 | 9 | |
Activates transient receptor potential melastatin 8 (TRPM8) which is involved in menthol and cold-induced signaling, a mechanism distinct from olfactory reception, thereby potentially reducing the sensitivity of OR13C4 to its specific ligands. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Agonist of the transient receptor potential vanilloid 1 (TRPV1) channel, a receptor unrelated to olfactory signaling pathways, potentially diminishing the perception of odorants by OR13C4 by modulating sensory neuron activity. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Acts on the transient receptor potential cation channel, subfamily A, member 1 (TRPA1), which is implicated in sensory mechanisms independent of olfactory G protein-coupled receptors like OR13C4, potentially altering OR13C4 mediated olfaction. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $43.00 $66.00 $117.00 | 3 | |
Stimulates TRPA1 channels, potentially decreasing OR13C4 activity by providing an alternative olfactory stimulus that interferes with OR13C4's normal odorant detection and signal transduction mechanisms. | ||||||
(±)-Menthol | 89-78-1 | sc-250299 sc-250299A | 100 g 250 g | $38.00 $67.00 | ||
A known agonist of TRPM8, which could potentially desensitize olfactory receptors such as OR13C4 by activating overlapping or adjacent sensory pathways, thus reducing OR13C4's sensitivity to its odorants. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Affects the olfactory epithelium and receptors such as OR13C4, potentially leading to reduced binding of OR13C4 to odorants through alteration of the olfactory receptor environment. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Can cause olfactory dysfunction and might decrease OR13C4 activity by altering the olfactory epithelium or receptor sites, reducing the ability of OR13C4 to detect and respond to its specific odorants. | ||||||
Dihydrocapsaicin | 19408-84-5 | sc-202578 sc-202578A | 10 mg 50 mg | $51.00 $153.00 | 1 | |
Could lead to reduced OR13C4 activity by modulating sensory neuron activity and potentially decreasing the sensitivity of OR13C4 to odorant molecules. | ||||||