Olfr917 Activators
Olfr917 is a member of the olfactory receptor protein family, playing a vital role in the olfactory system's ability to detect and differentiate various odorant molecules. As a G-protein coupled receptor (GPCR), Olfr917 is integral to the mechanism that translates chemical stimuli into neural signals, allowing for the perception of scents. The functional activation of Olfr917, like other olfactory receptors, is central to this olfactory signal transduction process. Activation is initiated when specific chemical compounds, which function as odorants, bind to Olfr917. This binding results in a conformational change in the protein, which is the primary trigger for signal transduction.
The specificity of interaction between Olfr917 and these odorant molecules is crucial for the selective detection of odors. Each olfactory receptor, including Olfr917, possesses unique binding sites that correspond structurally with particular odorant molecules. When a molecule such as butyl benzoate or ethyl cinnamate binds to Olfr917, it induces a structural alteration in the receptor. This alteration leads to the activation of the receptor's associated G-proteins, initiating a series of intracellular signaling events. These events typically involve the generation of secondary messengers, such as cyclic AMP and an increase in intracellular calcium levels. These messengers amplify the olfactory signal, resulting in a neural response. This mechanism of activation allows for the precise detection and differentiation of a wide array of odors, underlining the sophistication and specificity of the olfactory system. Moreover, Olfr917's ability to be activated by various chemicals, each with distinct structural characteristics, exemplifies the broad specificity inherent to olfactory receptors. This enables the olfactory system to discern an array of odorant molecules, each providing a unique olfactory experience. The precise interaction of these chemicals with Olfr917 is essential for the accurate functioning of the olfactory system, facilitating the detection and perception of odors. This interaction is fundamental to our sense of smell, significantly influencing our daily life and interactions with our environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Phenylethyl propionate | 122-70-3 | sc-265896 | 50 g | $57.00 | ||
Propyl phenylacetate, known for its sweet and floral scent, activates Olfr917 by binding to its olfactory receptor sites. This binding triggers a change in the receptor's conformation, activating associated G-protein coupled signaling pathways. These pathways, including the rise in intracellular calcium and cyclic AMP levels, are crucial for the functional activation and proper signal transduction of Olfr917. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl vanillin activates Olfr917 by binding to its olfactory receptor sites, causing a conformational change in the receptor. This change facilitates the activation of G-protein coupled pathways, resulting in intracellular signaling events. The increase in cyclic AMP, particularly, is essential for the functional activation of Olfr917, playing a key role in the perception of ethyl vanillin's sweet vanilla-like odor. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, a compound with a wintergreen odor, activates Olfr917 by interacting with its specific olfactory receptor binding sites. This interaction causes a change in the receptor's structure, triggering the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is vital for the functional activation of Olfr917, enhancing the perception of its minty scent. | ||||||
Isobutyl benzoate | 120-50-3 | sc-353634 sc-353634A | 25 g 250 g | $23.00 $74.00 | ||
Isobutyl benzoate activates Olfr917 by binding to its olfactory receptor sites, causing a conformational change. This interaction facilitates the activation of G-protein coupled pathways, leading to a series of intracellular signaling events. These events, particularly the increase in cyclic AMP, are essential for the functional activation of Olfr917, contributing to the perception of its sweet and aromatic odor. | ||||||