OATP-C Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Estropipate | 7280-37-7 | sc-203946 | 50 mg | $107.00 | 1 | |
Estropipate is a distinctive compound that engages with OATP transporters, showcasing a unique binding affinity due to its structural conformation. Its interactions are characterized by competitive inhibition, which alters substrate transport efficiency. The presence of specific functional groups enhances its solubility and permeability, influencing the kinetics of organic anion transport. Furthermore, its molecular interactions can modulate cellular signaling pathways, impacting overall transport dynamics. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporin A may inhibit OATP-C expression by interacting with nuclear receptors that regulate the SLCO1B1 gene transcription. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Rifampicin can downregulate OATP-C by activating pregnane X receptor (PXR), which in turn may decrease the transcription of the SLCO1B1 gene. | ||||||
Chrysin | 480-40-0 | sc-204686 | 1 g | $37.00 | 13 | |
Chrysin is a flavonoid that might inhibit OATP-C by modulating various signaling pathways that influence SLCO1B1 gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin may suppress the expression of OATP-C through its anti-inflammatory effects, potentially altering SLCO1B1 gene transcription. | ||||||
Phloretin | 60-82-2 | sc-3548 sc-3548A | 200 mg 1 g | $63.00 $250.00 | 13 | |
Phloretin, found in apples, may decrease OATP-C expression by affecting cellular signaling that regulates the SLCO1B1 gene. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $56.00 $240.00 $815.00 $1305.00 | 4 | |
As a macrolide antibiotic, erythromycin may inhibit OATP-C expression through its interactions with hepatic cellular mechanisms that control gene expression. | ||||||
Clotrimazole | 23593-75-1 | sc-3583 sc-3583A | 100 mg 1 g | $41.00 $56.00 | 6 | |
Clotrimazole might downregulate OATP-C expression by interfering with pathways that regulate the SLCO1B1 gene at the transcriptional level. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $51.00 $292.00 | 3 | |
Progesterone could modulate OATP-C levels by hormonal regulation of gene expression, potentially altering the transcription of the SLCO1B1 gene. | ||||||
Nicardipine hydrochloride | 54527-84-3 | sc-202731 sc-202731A | 1 g 5 g | $32.00 $81.00 | 5 | |
Nicardipine may inhibit the expression of OATP-C through calcium-channel dependent signaling pathways that affect the SLCO1B1 gene. | ||||||