Date published: 2025-12-6

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Nitric Oxide Donors

Santa Cruz Biotechnology now offers a broad range of nitric oxide donors for use in various applications. Nitric oxide (NO) donors are chemical compounds that release nitric oxide, a vital signaling molecule involved in numerous physiological and pathological processes. These donors are crucial tools in scientific research for studying the roles of nitric oxide in vascular biology, neurotransmission, immune response, and cellular signaling. Researchers use nitric oxide donors to investigate the mechanisms by which NO regulates blood flow, modulates neurotransmitter release, and mediates immune defense mechanisms. These compounds are also employed in exploring the pathophysiology of conditions such as hypertension, neurodegenerative diseases, and inflammatory disorders. By providing a controlled and sustained release of nitric oxide, NO donors enable the detailed study of its biological effects and the elucidation of NO-dependent signaling pathways. Furthermore, nitric oxide donors are instrumental in developing experimental models to understand NO's role in various cellular processes and to identify new fundemental targets. By offering a comprehensive selection of high-quality nitric oxide donors, Santa Cruz Biotechnology supports advanced research in physiology and cell biology. These products empower scientists to achieve precise and reproducible results, driving advancements in our understanding of nitric oxide biology and its applications in health and disease. View detailed information on our available nitric oxide donors by clicking on the product name.

Items 11 to 20 of 56 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Diethylamine NONOate

372965-00-9sc-202575
sc-202575A
sc-202575B
sc-202575C
10 mg
50 mg
100 mg
500 mg
$37.00
$111.00
$199.00
$882.00
1
(1)

Diethylamine NONOate acts as a nitric oxide donor through a unique mechanism involving the cleavage of its N-O bond, leading to the release of nitric oxide. Its molecular structure allows for selective interactions with various nucleophiles, enhancing its reactivity profile. The compound exhibits notable stability under varying conditions, which influences its release kinetics. Additionally, its electron-rich environment contributes to its ability to participate in diverse redox reactions, making it an intriguing candidate for studying nitric oxide's role in chemical processes.

NOC-5

146724-82-5sc-202248A
sc-202248B
sc-202248
sc-202248C
1 mg
5 mg
10 mg
25 mg
$59.00
$156.00
$216.00
$410.00
5
(1)

NOC-5 functions as a nitric oxide donor by facilitating the generation of nitric oxide through a distinctive pathway involving the activation of its nitroso group. This compound showcases a high degree of reactivity due to its unique electronic configuration, which promotes rapid interactions with biological and chemical substrates. Its stability in diverse environments allows for controlled release, while its ability to engage in complex coordination chemistry enhances its potential for exploring nitric oxide's multifaceted roles in various reactions.

Spermine NONOate

136587-13-8sc-202816
sc-202816A
5 mg
25 mg
$52.00
$192.00
5
(1)

Spermine NONOate acts as a nitric oxide donor by undergoing hydrolysis, leading to the release of nitric oxide in a controlled manner. Its unique polyamine structure allows for specific interactions with cellular components, influencing signaling pathways. The compound exhibits notable reaction kinetics, characterized by a rapid initial release followed by a sustained output, making it an intriguing subject for studying nitric oxide's diverse biological effects and mechanisms.

NOC-7

146724-84-7sc-202249
10 mg
$210.00
5
(1)

NOC-7 functions as a nitric oxide donor through a distinct mechanism involving the cleavage of its nitro group, facilitating the release of nitric oxide. Its unique structural features enable selective interactions with metal ions, enhancing its reactivity. The compound demonstrates a biphasic release profile, with an initial burst followed by a gradual release, allowing for nuanced modulation of nitric oxide levels. This behavior makes it a compelling candidate for exploring the dynamics of nitric oxide in various chemical environments.

Sodium nitroprusside dihydrate

13755-38-9sc-203395
sc-203395A
sc-203395B
1 g
5 g
100 g
$42.00
$83.00
$155.00
7
(1)

Sodium nitroprusside dihydrate acts as a nitric oxide donor by undergoing photolytic decomposition, which liberates nitric oxide in a controlled manner. Its coordination with transition metals enhances its stability and reactivity, allowing for specific interactions that influence reaction kinetics. The compound exhibits a unique solubility profile, facilitating its dispersion in various media, and its ability to form complexes with ligands can modulate its release characteristics, making it an intriguing subject for studying nitric oxide dynamics.

JS-K

205432-12-8sc-211683
sc-211683A
5 mg
25 mg
$153.00
$530.00
14
(1)

JS-K functions as a nitric oxide donor through a unique mechanism involving the release of nitric oxide via a reductive pathway. Its structure allows for selective interactions with biological thiols, leading to the formation of stable adducts that influence its reactivity. The compound's distinct electron-donating properties enhance its ability to participate in redox reactions, while its solubility in organic solvents facilitates diverse experimental applications, making it a compelling candidate for exploring nitric oxide signaling.

Piloty′s Acid

599-71-3sc-205436
sc-205436A
500 mg
1 g
$20.00
$32.00
(0)

Piloty's Acid acts as a nitric oxide donor by undergoing hydrolysis, which generates nitric oxide in a controlled manner. Its unique structure promotes interactions with metal ions, enhancing its reactivity and stability in various environments. The compound exhibits distinct kinetic properties, allowing for a gradual release of nitric oxide, which can be fine-tuned by altering reaction conditions. This behavior makes it an intriguing subject for studying nitric oxide dynamics in complex systems.

GEA 5583

sc-205946
sc-205946A
10 mg
50 mg
$41.00
$164.00
(0)

GEA 5583 functions as a nitric oxide donor through a distinctive mechanism involving the cleavage of specific bonds, leading to the release of nitric oxide. Its molecular architecture facilitates unique interactions with biological substrates, influencing reaction pathways and enhancing its efficacy. The compound's reactivity is characterized by rapid kinetics under certain conditions, allowing for precise modulation of nitric oxide release, making it a compelling candidate for exploring redox processes in various chemical environments.

PROLI NONOate

178948-42-0sc-222190
sc-222190A
sc-222190B
10 mg
50 mg
100 mg
$45.00
$206.00
$360.00
(0)

PROLI NONOate acts as a nitric oxide donor by undergoing hydrolysis, which generates nitric oxide through a controlled release mechanism. Its structural features promote selective interactions with target molecules, influencing downstream signaling pathways. The compound exhibits notable stability in aqueous environments, allowing for sustained nitric oxide production. Its reaction kinetics are finely tuned, enabling it to participate in diverse biochemical processes while maintaining a balance between reactivity and stability.

Fructose-SNAP-1

sc-221631
5 mg
$76.00
(0)

Fructose-SNAP-1 functions as a nitric oxide donor through a unique mechanism that involves the cleavage of its ester bonds, facilitating the release of nitric oxide in a regulated manner. Its molecular structure enhances solubility and promotes specific interactions with biological targets, influencing various signaling cascades. The compound's reaction kinetics are characterized by a rapid onset of activity, while its stability in physiological conditions allows for prolonged nitric oxide availability, making it a versatile agent in biochemical contexts.