NDUFB10 Inhibitors
The class of chemical compounds known as NDUFB10 Inhibitors represents a group of molecules designed or discovered to interact with and inhibit the function of the NDUFB10 protein, a subunit of the mitochondrial respiratory complex I. Mitochondrial complex I, also known as NADH:ubiquinone oxidoreductase, plays a crucial role in cellular respiration by mediating the transfer of electrons from NADH to ubiquinone. NDUFB10 is one of the numerous subunits that constitute this multiprotein complex, and its function is essential for maintaining proper electron transfer and energy production within the mitochondria.
NDUFB10 Inhibitors can vary widely in their chemical structures and mechanisms of action. Some inhibitors, such as rotenone and piericidin A, function by directly binding to complex I, disrupting its electron transfer chain, and ultimately impeding the flow of electrons through the respiratory chain. Others, like metformin or rotenone, may indirectly impact NDUFB10 by altering mitochondrial function or influencing signaling pathways associated with mitochondrial activity. This diverse class of compounds offers researchers valuable tools for studying the complex interplay within the mitochondrial electron transport chain and furthering our understanding of cellular bioenergetics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Inhibits NDUFB10 by binding to Complex I and blocking electron transfer. | ||||||
Piericidin A | 2738-64-9 | sc-202287 | 2 mg | $291.00 | 24 | |
Disrupts NDUFB10 function by targeting Complex I of the mitochondrial electron transport chain. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Affects NDUFB10 indirectly by modulating mitochondrial function through TRPV1 receptors. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
May indirectly inhibit NDUFB10 by altering mitochondrial function and cellular energy metabolism. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $290.00 | ||
Targets the mitochondrial respiratory chain, potentially affecting NDUFB10 activity. | ||||||
Amodiaquine | 86-42-0 | sc-207282 | 10 mg | $342.00 | 1 | |
Has been studied for its potential effects on mitochondrial function, which may impact NDUFB10. | ||||||
Diphenyleneiodonium chloride | 4673-26-1 | sc-202584E sc-202584 sc-202584D sc-202584A sc-202584B sc-202584C | 10 mg 25 mg 50 mg 100 mg 250 mg 500 mg | $151.00 $136.00 $317.00 $405.00 $944.00 $1837.00 | 24 | |
Inhibits mitochondrial electron transport, possibly affecting NDUFB10 activity. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
Modulates mitochondrial function and may indirectly influence NDUFB10. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
May impact mitochondrial function, potentially affecting NDUFB10 activity. | ||||||