NAGA Substrates

Santa Cruz Biotechnology now offers a broad range of NAGA Substrates for use in various applications. Alpha-N-acetylgalactosaminidase (NAGA) is an enzyme that plays a critical role in the lysosomal degradation of glycolipids and glycoproteins by hydrolyzing terminal N-acetylgalactosamine residues. This enzyme is essential for the breakdown and recycling of complex molecules within cells, particularly in the process of lysosomal storage and maintenance of cellular homeostasis. NAGA Substrates are invaluable tools in scientific research, enabling the detailed study of NAGA activity and its role in cellular metabolism. Researchers use these substrates to assess the enzymatic function of NAGA under various conditions, explore the biochemical pathways involving glycosaminoglycans and glycoproteins, and investigate the impact of NAGA activity on cellular and organismal health. These substrates are widely employed in studies of lysosomal storage disorders, where deficiencies in NAGA activity can lead to the accumulation of undegraded substrates, resulting in severe cellular dysfunction. Additionally, NAGA Substrates are used in screening assays to identify potential modulators of enzyme activity, offering insights into therapeutic strategies for conditions associated with abnormal lysosomal function. The availability of these substrates has significantly advanced research in biochemistry, molecular biology, and cell biology, providing critical insights into the complex processes governing cellular metabolism and the role of lysosomal enzymes in health and disease. View detailed information on our available NAGA Substrates by clicking on the product name.