MUSTN1 Activators
MUSTN1 Activators belong to a distinct chemical class primarily associated with their role in modulating specific cellular processes and molecular pathways. These compounds are characterized by their ability to interact with MUSTN1, a critical protein involved in various cellular functions. MUSTN1, short for Muscle, Skeletal, and Cardiac Uncoupling Protein 1, plays an essential role in regulating the uncoupling of mitochondria, which is the process of separating the production of cellular energy (ATP) from the generation of heat. MUSTN1 is primarily expressed in muscle tissues, including skeletal and cardiac muscles, where it has been found to have a profound influence on metabolic homeostasis.
MUSTN1 Activators are designed to enhance the activity of MUSTN1, leading to increased mitochondrial uncoupling. This heightened uncoupling process can have significant implications for cellular metabolism and energy balance. By promoting mitochondrial uncoupling, these activators may influence the overall energy expenditure within muscle cells, potentially impacting factors such as thermogenesis and fuel utilization. Furthermore, the modulation of MUSTN1 activity by these compounds may also have ramifications for the regulation of reactive oxygen species (ROS) production and oxidative stress, as mitochondrial uncoupling can influence these aspects of cellular physiology. Overall, MUSTN1 Activators represent a chemical class with the potential to fine-tune the intricate balance of cellular energy regulation, opening avenues for further research into their broader biological implications.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA is a histone deacetylase (HDAC) inhibitor that can alter chromatin structure by increasing histone acetylation, potentially reactivating silenced genes like MUSTN1. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This compound is a DNA demethylating agent that can reactivate genes that were silenced through DNA methylation, including potentially MUSTN1. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that can influence gene expression by binding to glucocorticoid receptors and modulating the activity of various transcription factors. It may indirectly affect MUSTN1 expression through these transcriptional changes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can regulate the expression of numerous genes, including those involved in skeletal development. It may indirectly affect MUSTN1 by modulating retinoic acid response elements in the gene's regulatory regions. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid is an HDAC inhibitor like TSA, and it can modify chromatin structure, potentially activating genes that were previously silenced, including MUSTN1. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide is a protein synthesis inhibitor. While it doesn't directly activate genes, it can affect gene expression by blocking translation and protein turnover, which may lead to changes in gene expression over time. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase and increases cAMP levels, which can affect gene expression through cAMP-dependent pathways. Its specific effects on MUSTN1 would depend on the presence of relevant regulatory elements. | ||||||