MTF-1 Activators
MTF-1 Activators are a class of chemicals that enhance the functional activity of MTF-1 primarily through the direct binding of these chemicals to MTF-1, which triggers its translocation to the nucleus. Once in the nucleus, MTF-1 binds to metal response elements (MREs) and enhances the transcription of target genes. These activators, which include zinc sulphate, cadmium chloride, and nickel chloride, bind directly to MTF-1, causing it to move to the nucleus and bind to MREs. This binding event causes the enhancement of target gene transcription, leading to the activation of MTF-1.
Furthermore, MTF-1 Activators include chemicals such as copper sulfate, cobalt chloride, and sodium arsenite, which can also bind to MTF-1, triggering its translocation to the nucleus and subsequent interaction with MREs. This binding event causes the enhancement of target gene transcription, leading to the activation of MTF-1. Selenium dioxide, lead nitrate, mercury chloride, silver nitrate, thallium nitrate, and tin chloride are also part of the MTF-1 Activators class. These compounds bind to MTF-1, causing it to translocate to the nucleus and bind to MREs. The binding of MTF-1 to these elements enhances the transcription of target genes, leading to an increase in MTF-1 functional activity. Thus, through direct binding and subsequent nuclear translocation of MTF-1, these compounds can enhance the functional activity of MTF-1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is a known activator of MTF-1. It binds directly to MTF-1, inducing its translocation to the nucleus where it can bind to metal response elements (MREs) and enhance transcription of target genes. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
Cadmium is a heavy metal that can activate MTF-1. Similar to zinc, it binds to MTF-1 causing its translocation to the nucleus and subsequent activation of target gene transcription. | ||||||
Nickel(II) chloride | 7718-54-9 | sc-236169 sc-236169A | 100 g 500 g | $68.00 $188.00 | ||
Nickel is another heavy metal that can activate MTF-1. It triggers MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $46.00 $122.00 $189.00 | 3 | |
Although high levels of copper can inhibit MTF-1, moderate levels can activate MTF-1, leading to its nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $64.00 $176.00 | 7 | |
Cobalt is a heavy metal that can activate MTF-1. It causes MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Sodium arsenite can activate MTF-1, leading to its nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
Selenium dioxide can activate MTF-1. It causes MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Lead (II) nitrate | 10099-74-8 | sc-211724 sc-211724A | 100 g 500 g | $40.00 $88.00 | ||
Lead nitrate can activate MTF-1. It triggers MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $114.00 $378.00 $1081.00 | 1 | |
Silver nitrate can activate MTF-1. It causes MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||
Thallium(I) Nitrate | 10102-45-1 | sc-264405 sc-264405A | 25 g 100 g | $100.00 $295.00 | ||
Thallium nitrate can activate MTF-1. It triggers MTF-1 nuclear translocation and binding to MREs, enhancing target gene transcription. | ||||||