MSMP Inhibitors primarily functions to modulate various cellular signaling pathways, related to MSMP's role or expression. Among the notable compounds in this category, Gefitinib stands out as an EGFR inhibitor. The EGFR signaling cascade is intimately connected to cellular growth, proliferation, and survival, suggesting that its modulation can indirectly influence MSMP-associated processes. Likewise, compounds such as PD98059 and U0126 are recognized for their inhibitory effects on MEK, subsequently affecting the MAPK/ERK pathway.
Furthermore, the PI3K/Akt pathway, a cornerstone for cell survival and proliferation, can be targeted using inhibitors like LY294002, Wortmannin, Ipatasertib, and ZSTK474. By adjusting this signaling axis, these inhibitors offer a strategy to influence cellular processes linked with MSMP. Rapamycin's role as an mTOR inhibitor signifies its capacity to modulate cell growth and metabolic pathways, which can be linked with MSMP. Lastly, Palbociclib's ability to inhibit CDK4/6 offers an approach to control cell cycle progression.
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