mGluR-1a Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ro 67-4853 | 302841-89-0 | sc-362790 sc-362790A | 10 mg 50 mg | $120.00 $490.00 | ||
Ro 67-4853 acts as a selective modulator of mGluR1a, exhibiting unique binding characteristics that enhance receptor affinity. Its distinct molecular interactions involve hydrophobic contacts and van der Waals forces, which promote receptor dimerization and influence downstream signaling cascades. The compound's kinetic profile reveals a rapid onset of action, allowing for precise modulation of intracellular pathways, ultimately affecting neuronal communication and synaptic plasticity. | ||||||
L-Cysteinesulfinic acid | 1115-65-7 | sc-203620 sc-203620A sc-203620B sc-203620C | 100 mg 250 mg 500 mg 1 g | $204.00 $459.00 $612.00 $1040.00 | ||
L-Cysteinesulfinic acid serves as a potent allosteric modulator of mGluR1a, engaging in specific electrostatic interactions that stabilize receptor conformation. Its unique structural features facilitate the formation of transient complexes, enhancing receptor sensitivity to endogenous ligands. The compound exhibits a distinctive reaction kinetics profile, characterized by a gradual activation phase that fine-tunes signaling pathways, thereby influencing cellular responses and synaptic dynamics. | ||||||
(2S,4R)-gamma-Hydroxyglutamic acid | 2485-33-8 | sc-283521 sc-283521A | 10 mg 50 mg | $196.00 $568.00 | ||
(2S,4R)-gamma-Hydroxyglutamic acid acts as a selective modulator of mGluR1a, exhibiting unique stereochemical properties that enhance its binding affinity. Its hydroxyl group participates in hydrogen bonding, promoting receptor activation through conformational changes. The compound's distinct molecular interactions lead to altered signaling cascades, influencing neuronal excitability and synaptic plasticity. Its kinetic behavior is marked by a rapid onset of action, contributing to dynamic cellular responses. | ||||||
(RS)-3,5-DHPG | 19641-83-9 | sc-205496 sc-205496A | 10 mg 50 mg | $152.00 $632.00 | ||
(RS)-3,5-DHPG is a potent agonist of the mGluR1a receptor, characterized by its ability to induce specific conformational shifts in the receptor's structure. This compound engages in unique electrostatic interactions that stabilize the receptor-ligand complex, enhancing signal transduction efficiency. Its rapid kinetics facilitate swift modulation of intracellular pathways, impacting calcium signaling and neurotransmitter release, thereby influencing synaptic dynamics and neuronal communication. | ||||||
(S)-3-Hydroxyphenylglycine | 71301-82-1 | sc-204254 sc-204254A | 10 mg 50 mg | $225.00 $930.00 | ||
(S)-3-Hydroxyphenylglycine acts as a selective agonist for the mGluR1a receptor, exhibiting a unique binding affinity that promotes distinct allosteric modulation. This compound is known for its ability to form hydrogen bonds with key amino acid residues, which enhances receptor activation. Its interaction profile leads to altered downstream signaling cascades, particularly affecting phosphoinositide turnover and intracellular calcium mobilization, thereby fine-tuning synaptic plasticity and neuronal excitability. | ||||||
cis-ACPD | 39026-63-6 | sc-202102 | 5 mg | $60.00 | ||
Cis-ACPD is a potent agonist for the mGluR1a receptor, characterized by its ability to induce receptor dimerization, which enhances signaling efficacy. This compound uniquely interacts with the receptor's transmembrane domains, facilitating conformational changes that activate G-protein coupled pathways. Its kinetic profile reveals rapid onset and prolonged action, influencing neurotransmitter release and modulating synaptic strength through intricate feedback mechanisms. | ||||||