melanopsin Inhibitors
The chemical class of Melanopsin Inhibitors includes a range of specific compounds that can potentially suppress or modulate the activity of Melanopsin, primarily through effects on the phototransduction pathway, retinal health, and related cellular processes. Melatonin, TPEN, Tetrathiomolybdate, Bexarotene, and Citral are included for their potential to modulate key aspects of Melanopsin activation, such as the availability of essential cofactors and the function of Vitamin A-related pathways.
Luteolin, Norbixin, Baclofen, L-NAME, Cyx3, Morphine, and Verapamil are considered for their roles in influencing various signaling pathways and cellular processes that could impact Melanopsin function, including flavonoid effects, GABAergic pathway modulation, nitric oxide synthesis inhibition, blue light filtering, opioid-related modulation, and calcium signaling regulation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $65.00 $73.00 $218.00 $697.00 $1196.00 $3574.00 | 16 | |
Known to influence circadian rhythms and light perception, melatonin could potentially counteract Melanopsin's effects. | ||||||
TPEN | 16858-02-9 | sc-200131 | 100 mg | $130.00 | 10 | |
A specific zinc chelator, potentially affecting zinc-dependent processes in the retina and indirectly inhibiting Melanopsin activity. | ||||||
Ammonium tetrathiomolybdate | 15060-55-6 | sc-239242 sc-239242A sc-239242B sc-239242C | 1 g 10 g 25 g 50 g | $47.00 $203.00 $421.00 $525.00 | ||
A copper chelator that could sequester copper, indirectly affecting Melanopsin activity by influencing copper-dependent processes. | ||||||
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $55.00 $250.00 | 6 | |
A retinoid X receptor agonist that can modulate the action of Vitamin A, potentially affecting Melanopsin. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Known to inhibit retinoic acid synthesis, potentially reducing Melanopsin activity. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
A flavonoid that may have inhibitory effects on various cellular processes and could indirectly affect Melanopsin function. | ||||||
(±)-Baclofen | 1134-47-0 | sc-200464 sc-200464A | 1 g 5 g | $56.00 $258.00 | ||
A GABA receptor agonist, which could potentially modulate Melanopsin activity through retinal GABAergic pathways. | ||||||
L-NG-Nitroarginine Methyl Ester (L-NAME) | 51298-62-5 | sc-200333 sc-200333A sc-200333B | 1 g 5 g 25 g | $48.00 $107.00 $328.00 | 45 | |
A nitric oxide synthase inhibitor, potentially impacting retinal signaling and Melanopsin activity. | ||||||
Chlorhexidine | 55-56-1 | sc-252568 | 5 g | $103.00 | 3 | |
A compound that filters blue light, potentially inhibiting Melanopsin activation. | ||||||