Date published: 2025-12-10

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MEL-1 Activators

Santa Cruz Biotechnology now offers a broad range of MEL-1 Activators for use in various applications. Melatonin receptors, particularly the MEL-1 subtype, are G-protein-coupled receptors that play a pivotal role in regulating circadian rhythms, sleep-wake cycles, and various other physiological processes influenced by the hormone melatonin. These receptors are integral to the body's ability to adapt to changes in light and dark cycles, thus helping to maintain a healthy circadian rhythm. MEL-1 Activators are essential tools in scientific research, allowing researchers to enhance the activity of these receptors to study their specific roles in biological rhythms and how they interact with other signaling pathways. By activating MEL-1 receptors, scientists can explore how these receptors influence behavior, mood, and physiological functions, as well as their involvement in adapting to environmental changes. These activators are widely used in studies focused on understanding the molecular mechanisms underlying circadian biology, the impact of disrupted melatonin signaling on health, and the potential of targeting MEL-1 receptors to manage disorders related to circadian rhythm disturbances. Additionally, MEL-1 Activators are valuable for research into the effects of melatonin and its analogs on various biological systems, providing insights into how modulating melatonin receptor activity can influence a wide range of physiological processes. The availability of these activators has significantly advanced research in chronobiology, neuroscience, and endocrinology, offering crucial tools for studying the regulation of biological clocks and their broader implications for health. View detailed information on our available MEL-1 Activators by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Methoxy-N-cyclopropanoyltryptamine

139564-01-5sc-221033
5 mg
$80.00
(0)

5-Methoxy-N-cyclopropanoyltryptamine acts as a potent MEL-1, showcasing intriguing molecular interactions that enhance its reactivity profile. Its unique cyclopropanoyl moiety introduces strain, facilitating rapid electrophilic attacks on nucleophiles. This compound exhibits selective binding affinities, influencing downstream signaling pathways. The presence of the methoxy group further modulates electronic properties, optimizing its interaction dynamics in complex biochemical environments.

N-Acetyltryptamine

1016-47-3sc-202233
sc-202233A
10 mg
50 mg
$117.00
$495.00
(1)

N-Acetyltryptamine functions as a notable MEL-1, characterized by its ability to engage in specific hydrogen bonding interactions that stabilize its conformation. The acetyl group enhances lipophilicity, promoting membrane permeability and influencing its kinetic behavior in biological systems. Its structural features allow for selective receptor binding, potentially altering downstream molecular cascades. Additionally, the compound's unique electronic distribution plays a crucial role in modulating its reactivity and interaction with various biomolecules.

2-Iodomelatonin

93515-00-5sc-203463
sc-203463A
10 mg
50 mg
$72.00
$264.00
2
(1)

2-Iodomelatonin, as a MEL-1, exhibits intriguing molecular interactions due to the presence of the iodine atom, which introduces unique steric and electronic effects. This halogen substitution enhances its lipophilic character, facilitating interactions with lipid membranes. The compound's distinct electronic configuration allows for specific binding affinities, influencing receptor dynamics and downstream signaling pathways. Its reactivity is further modulated by the iodine's polarizability, impacting its behavior in various chemical environments.

GR 135531

190277-13-5sc-203981
sc-203981A
10 mg
50 mg
$320.00
$1400.00
(0)

GR 135531, classified as a MEL-1, showcases remarkable reactivity as an acid halide, characterized by its ability to form stable acyl derivatives through nucleophilic acyl substitution. The presence of the halide enhances electrophilicity, promoting rapid reaction kinetics with amines and alcohols. Its unique steric profile allows for selective interactions, influencing the formation of specific reaction products. Additionally, the compound's solubility in organic solvents underscores its utility in diverse synthetic pathways.