Mat1 inhibitors belong to a specific class of compounds designed to modulate the activity of Mat1, a protein that plays a critical role in cell cycle progression and the regulation of DNA replication. These inhibitors are meticulously developed to interact with Mat1, affecting its function in coordinating the transition between different phases of the cell cycle. Mat1 is known to be associated with cellular processes such as DNA synthesis and the regulation of checkpoint mechanisms. By selectively engaging with Mat1, these inhibitors aim to influence cell cycle dynamics, DNA replication, and cell proliferation. Mat1 inhibitors can encompass a range of chemical structures, including small molecules or peptides, designed to effectively bind to Mat1's functional domains.
The primary purpose of developing Mat1 inhibitors is to investigate the intricate mechanisms by which Mat1 contributes to cell cycle progression and DNA replication. By modulating Mat1 activity, researchers can gain insights into how this protein orchestrates the precise timing of DNA synthesis and coordinates cell division. These inhibitors serve as essential tools for exploring the molecular events that govern cell cycle transitions and DNA replication checkpoints.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sinefungin | 58944-73-3 | sc-203263 sc-203263B sc-203263C sc-203263A | 1 mg 100 mg 1 g 10 mg | $271.00 $5202.00 $40368.00 $704.00 | 4 | |
Sinefungin is a natural nucleoside analog and a well-known inhibitor of MATIt resembles the structure of SAMe and competes with it for binding to the enzyme's active site. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
I3C is a phytochemical found in cruciferous vegetables and has been identified as a MAT1 inhibitor. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major polyphenol in green tea, has been suggested to inhibit MAT1 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a bioactive compound found in turmeric, has shown inhibitory effects on MAT1 in certain studies. | ||||||
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $122.00 | 1 | |
MTA-D is a synthetic derivative of MTA and has been studied for its potential as an MAT1 inhibitor. | ||||||