Date published: 2025-12-18

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Macrocycles

Santa Cruz Biotechnology now offers a broad range of macrocycles for use in various applications. Macrocycles, which are large ring molecules consisting of twelve or more atoms, are critical in scientific research due to their unique structural properties and diverse functionalities. These compounds have found extensive use in supramolecular chemistry, where their ability to form host-guest complexes makes them valuable for studying molecular recognition and self-assembly processes. Macrocycles are instrumental in materials science, as their robust frameworks and ability to encapsulate ions or molecules enable the development of advanced materials, such as sensors, catalysts, and nanomaterials. In organic synthesis, macrocycles serve as scaffolds for the construction of complex molecular architectures, facilitating the creation of compounds with specific properties and functions. Environmental chemists utilize macrocycles to develop selective binding agents for pollutant detection and removal, contributing to advancements in environmental remediation technologies. Additionally, macrocycles are crucial in the study of biological systems, where they mimic natural macrocyclic structures like enzymes and nucleic acids, providing insights into biological mechanisms and interactions. Their versatility and capability to undergo functional modifications make macrocycles indispensable tools in research, allowing scientists to explore new chemical spaces and design innovative solutions across various scientific disciplines. View detailed information on our available macrocycles by clicking on the product name.

Items 251 to 260 of 289 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Desmycosin

11032-98-7sc-500155
sc-500155A
100 mg
500 mg
$408.00
$1543.00
1
(1)

Desmycosin is a macrocyclic compound characterized by its intricate ring structure, which fosters unique intramolecular interactions. This configuration enhances its ability to form stable complexes with metal ions, influencing coordination chemistry. The compound exhibits notable conformational rigidity, which can affect its solubility and diffusion properties. Additionally, its distinct electronic distribution allows for selective reactivity in various chemical environments, impacting reaction rates and pathways.

4′-Carboxybenzo-15-crown-5

56683-55-7sc-233103
1 g
$200.00
(0)

4'-Carboxybenzo-15-crown-5 is a macrocyclic compound characterized by its ability to selectively complex with cations, particularly alkali and alkaline earth metals. The presence of carboxyl groups enhances its solubility and interaction with polar solvents, facilitating unique hydrogen bonding and dipole-dipole interactions. This compound exhibits notable conformational versatility, allowing it to optimize binding geometries, which significantly influences its ion transport kinetics and selectivity in complexation reactions.

Etioporphyrin I dihydrobromide

69150-58-9sc-235103
100 mg
$87.00
1
(0)

Etioporphyrin I dihydrobromide is a macrocyclic compound distinguished by its unique porphyrin structure, which allows for extensive π-π stacking interactions and coordination with metal ions. Its dihydrobromide form enhances solubility in polar solvents, promoting effective electron transfer processes. The compound exhibits remarkable stability and reactivity, facilitating diverse pathways in photochemical reactions and influencing its behavior in various catalytic systems.

1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane

23978-55-4sc-223066
1 g
$184.00
(0)

1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane is a macrocyclic compound characterized by its intricate ring structure, which fosters unique host-guest interactions. The presence of multiple nitrogen and oxygen atoms allows for strong hydrogen bonding and chelation with metal ions, enhancing its stability. This compound exhibits distinct conformational flexibility, influencing its reactivity in complexation reactions and facilitating selective binding in various chemical environments.

5,6,14,15-Dibenzo-1,4-dioxa-8,12-diazacyclopentadeca-5,14-diene

65639-43-2sc-256952
1 g
$300.00
(0)

5,6,14,15-Dibenzo-1,4-dioxa-8,12-diazacyclopentadeca-5,14-diene is a macrocyclic compound notable for its dual aromatic and heterocyclic features, which contribute to its unique electronic properties. The arrangement of nitrogen and oxygen atoms within the ring enhances its ability to engage in π-stacking interactions and coordinate with transition metals. This compound exhibits remarkable conformational adaptability, allowing it to participate in diverse catalytic pathways and complexation processes, making it a subject of interest in supramolecular chemistry.

Moxidectin

113507-06-5sc-224098
25 mg
$109.00
1
(1)

Moxidectin is a macrocyclic compound characterized by its intricate ring structure, which facilitates unique intramolecular interactions. The presence of multiple nitrogen and oxygen atoms within the cyclic framework enhances its ability to form hydrogen bonds and engage in host-guest chemistry. Its rigid conformation allows for selective binding to specific substrates, influencing reaction kinetics and enabling participation in various catalytic cycles. This compound's distinct electronic distribution also contributes to its reactivity in complexation and coordination chemistry.

Tylosin tartaric acid

sc-338732
1 g
$700.00
(0)

Tylosin tartaric acid is a macrocyclic compound distinguished by its unique cyclic architecture, which promotes specific molecular interactions through its stereochemistry. The presence of multiple functional groups within the ring enhances its capacity for chelation and coordination with metal ions, influencing its reactivity. Its conformational flexibility allows for dynamic interactions in solution, affecting solubility and stability, while also facilitating diverse reaction pathways in synthetic applications.

4′,4"(5")-Di-tert-butyldicyclohexano-18-crown-6

223719-29-7sc-252234
5 g
$530.00
(0)

4',4"(5")-Di-tert-butyldicyclohexano-18-crown-6 is a macrocyclic compound characterized by its intricate cyclic structure, which enables selective ion binding through its unique cavity size and shape. This compound exhibits remarkable host-guest chemistry, allowing it to form stable complexes with cations, particularly alkali metals. Its bulky tert-butyl groups contribute to steric hindrance, enhancing solubility in organic solvents and influencing its interaction dynamics in various chemical environments.

Benzo-12-crown-4

14174-08-4sc-227320
1 g
$64.00
(0)

Benzo-12-crown-4 is a macrocyclic compound notable for its ability to selectively encapsulate cations due to its well-defined cavity. This compound demonstrates exceptional ion selectivity, particularly for alkali metals, through strong coordination interactions. Its unique aromatic structure enhances π-π stacking interactions, influencing its solubility and reactivity in nonpolar solvents. The compound's conformational flexibility allows for dynamic host-guest interactions, making it a fascinating subject for studying molecular recognition and complexation behavior.

C-Methylcalix[4]resorcinarene

65338-98-9sc-234255
1 g
$216.00
(0)

C-Methylcalix[4]resorcinarene is a versatile macrocycle characterized by its unique bowl-shaped architecture, which facilitates selective host-guest interactions. Its multiple hydroxyl groups enable strong hydrogen bonding, enhancing its ability to form stable complexes with various anions and neutral molecules. The compound exhibits intriguing conformational dynamics, allowing it to adapt its structure for optimal binding. Additionally, its hydrophobic interior promotes encapsulation of guest species, making it a subject of interest in supramolecular chemistry.