LRP130 Inhibitors
LRP130 inhibitors belong to a specific chemical class of compounds designed to target and modulate the activity of LRP130, which is a protein involved in various cellular processes. LRP130, also known as LIM domain only protein 4 (LMO4), is a transcriptional co-regulator that plays a crucial role in regulating gene expression. It is characterized by its LIM domain, a protein-protein interaction motif that allows it to interact with other transcription factors and co-regulators to modulate the transcriptional activity of specific genes. LRP130 is known to be involved in diverse biological processes, including cell growth, differentiation, and survival, making it an attractive target for research and drug development.
LRP130 inhibitors are designed to specifically interfere with the activity of LRP130, either by preventing its interaction with other proteins or by modulating its function within the transcriptional machinery. These inhibitors are typically small molecules that can bind to LRP130 and disrupt its normal function, thereby affecting downstream gene expression patterns. By targeting LRP130, these compounds influence various cellular pathways and processes, which can have significant implications in the context of research and drug discovery. Researchers studying LRP130 inhibitors aim to better understand the molecular mechanisms of gene regulation and explore their applications in various biological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Rotenone inhibits mitochondrial complex I, which could indirectly affect mitochondrial protein expression. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Chloramphenicol inhibits mitochondrial protein synthesis by targeting bacterial ribosome-like mitochondrial ribosomes. | ||||||
Doxycycline monohydrate | 17086-28-1 | sc-263109 sc-263109A | 5 g 25 g | $74.00 $204.00 | 9 | |
Doxycycline inhibits mitochondrial protein synthesis at the ribosomal level, potentially reducing LRP130 levels. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Antimycin A inhibits mitochondrial complex III, possibly affecting overall mitochondrial function and gene expression. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Oligomycin inhibits ATP synthase, potentially impacting mitochondrial energy status and gene expression. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $170.00 $385.00 | 3 | |
Actinonin may impair mitochondrial function by inhibiting peptide deformylase, affecting protein maturation. | ||||||
Phenformin Hydrochloride | 834-28-6 | sc-219590 | 10 g | $119.00 | 4 | |
Phenformin, like metformin, activates AMPK potentially leading to decreased mitochondrial gene expression. | ||||||
Paraquat chloride | 1910-42-5 | sc-257968 | 250 mg | $168.00 | 7 | |
Paraquat generates reactive oxygen species, which can damage mitochondria and alter gene expression. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Mdivi-1 is a mitochondrial division inhibitor that may indirectly affect mitochondrial DNA expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, which is involved in the regulation of mitochondrial function and protein synthesis. | ||||||