LRP12 Inhibitors
LRP12 Inhibitors are a class of chemical compounds that specifically target and inhibit the LRP12 protein. LRP12, short for Low-Density Lipoprotein Receptor-Related Protein 12, is a transmembrane receptor protein that plays a significant role in various cellular processes, particularly those related to cell signaling and membrane trafficking. It is a part of the LDL receptor family, which is involved in the uptake and regulation of lipoprotein particles. LRP12 itself is a complex protein with multiple domains and regions that contribute to its diverse functions in various tissues and cell types.
LRP12 inhibitors has been driven by the need to better understand the biological roles of LRP12 and its involvement in various signaling pathways. By blocking LRP12 activity, these inhibitors allow researchers to dissect its specific functions within cells. These chemical compounds are designed to interact with LRP12 at the molecular level, disrupting its normal function and stopping it from participating in cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
Inhibits Wnt processing and secretion by blocking Porcupine, thereby potentially reducing LRP12-mediated signaling as LRP12 can be involved in Wnt signaling pathways. | ||||||
GW 9662 | 22978-25-2 | sc-202641 | 5 mg | $70.00 | 30 | |
A PPARγ antagonist that might impact LRP12 by modifying the transcription of genes that are downstream of LRP12’s signaling cascade. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which may indirectly affect LRP12 activity through the MAPK/ERK pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, which may indirectly affect LRP12 activity through the PI3K/Akt pathway. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
A Hedgehog signaling pathway inhibitor, which may affect LRP12 indirectly as Hedgehog signaling can intersect with LRP receptor-mediated pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Another MEK inhibitor that could indirectly affect LRP12 through the MAPK/ERK pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, which may indirectly influence LRP12 activity by affecting downstream signaling pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor, which may affect LRP12-related signaling pathways. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
An endocrine disruptor that can alter cellular signaling, possibly impacting LRP12-related pathways. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
An antiparasitic that also inhibits Wnt/β-catenin signaling and might, therefore, have an indirect effect on LRP12-related pathways. | ||||||