Kinase inhibitors like PD98059 and U0126 that target MEK to prevent the activation of the ERK pathway, to PI3K inhibitors like LY294002 and Wortmannin that disrupt AKT signaling. JNK inhibitor SP600125 and p38 MAPK inhibitor SB203580 target the MAPK signaling pathway, which is integral to many cellular functions including proliferation, differentiation, and stress responses.
Other members of this class include mTOR inhibitor Rapamycin, which affects cell growth and proliferation, and Bortezomib, a proteasome inhibitor that influences protein degradation pathways. Trichostatin A, a histone deacetylase inhibitor, alters gene expression patterns, potentially affecting the expression of LOC729801. Similarly, Thapsigargin, a SERCA inhibitor, disrupts calcium homeostasis, which can have wide-ranging effects on cellular functions that may involve LOC729801. QNZ can affect the transcription of a multitude of genes, potentially including those related to LOC729801. Lastly, Cyclosporin A acts on T-cell activation and other immune responses, which could indirectly influence LOC729801's activity or expression.
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