Date published: 2025-12-5

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Lipid Staining

Santa Cruz Biotechnology now offers a broad range of lipid staining chemicals for use in various applications. These specialized reagents are essential for the visualization and analysis of lipids in biological samples, playing a critical role in cell biology and biochemistry research. Lipid staining chemicals enable scientists to study the complex dynamics and distribution of lipids within cells and tissues, providing insights into cellular structure, membrane composition, and lipid metabolism. These stains are crucial for investigating lipid-related processes such as lipid storage, transport, and signaling, which are fundamental to understanding cell function and homeostasis. Researchers use lipid staining to differentiate between various types of lipids, including neutral lipids, phospholipids, and glycolipids, facilitating detailed studies of lipid droplets, membranes, and lipid-rich structures. The high sensitivity and specificity of these staining agents ensure accurate detection and quantification of lipids, enabling the detailed examination of lipid alterations in response to environmental changes or experimental treatments. By providing clear and reliable visualization of lipids, these chemicals support a wide range of applications in microscopy, flow cytometry, and high-throughput screening. The availability of high-quality lipid staining chemicals from Santa Cruz Biotechnology ensures reproducibility and consistency in experimental results, which is vital for advancing lipid research and expanding our understanding of lipid biology. View detailed information on our available lipid staining chemicals by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

9-Anthryldiazomethane

10401-59-9sc-214434
25 mg
$326.00
2
(1)

9-Anthryldiazomethane is a unique lipid that features a polycyclic aromatic structure, which contributes to its distinct photophysical properties. This compound exhibits strong π-π stacking interactions, enhancing its stability in lipid environments. Its reactive diazo group allows for selective functionalization, facilitating the study of lipid dynamics. Additionally, its hydrophobic nature promotes incorporation into lipid bilayers, influencing membrane characteristics and dynamics.

Nile Red

7385-67-3sc-203747
sc-203747A
sc-203747B
sc-203747C
10 mg
250 mg
1 g
5 g
$49.00
$120.00
$190.00
$860.00
24
(6)

Nile Red is a lipophilic dye characterized by its ability to selectively stain neutral lipids, thanks to its unique hydrophobic and polar regions. The compound exhibits strong fluorescence, which is enhanced in lipid-rich environments, allowing for sensitive detection of lipid droplets. Its molecular structure facilitates interactions with lipid membranes, promoting aggregation and influencing membrane fluidity. This behavior makes Nile Red a valuable tool for studying lipid metabolism and cellular lipid dynamics.

Fluorol Yellow 088

81-37-8sc-215052
sc-215052A
5 g
25 g
$256.00
$1209.00
25
(2)

Fluorol Yellow 088 is a highly lipophilic compound known for its distinctive fluorescence properties, which are significantly amplified in lipid-rich environments. Its unique structure allows for effective partitioning into lipid bilayers, influencing membrane characteristics and dynamics. The compound's interactions with lipid molecules can alter their organization, potentially affecting cellular processes. Additionally, its stability and reactivity in various lipid contexts make it a notable subject for studies on lipid behavior and interactions.

N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl)phenylammonium p-toluenesulfonate

115534-33-3sc-215501
5 mg
$120.00
5
(1)

N,N,N-Trimethyl-4-(6-phenyl-1,3,5-hexatrien-1-yl)phenylammonium p-toluenesulfonate exhibits remarkable amphiphilic properties, facilitating its integration into lipid membranes. Its cationic nature promotes electrostatic interactions with negatively charged lipid headgroups, enhancing membrane fluidity and stability. The compound's unique conjugated system contributes to its photophysical behavior, allowing for energy transfer processes within lipid matrices, which can influence membrane dynamics and organization.

3,3′-Dioctadecyloxacarbocyanine perchlorate

34215-57-1sc-214168
25 mg
$133.00
7
(0)

3,3′-Dioctadecyloxacarbocyanine perchlorate is a highly lipophilic compound characterized by its extensive hydrocarbon chains, which enhance its affinity for lipid bilayers. This dye exhibits strong π-π stacking interactions, leading to unique aggregation behavior within lipid environments. Its distinct electronic properties enable effective resonance energy transfer, influencing the optical characteristics of lipid membranes and potentially altering their structural integrity and dynamics.

1,6-Diphenyl-1,3,5-hexatriene

1720-32-7sc-213545
sc-213545A
1 g
5 g
$77.00
$240.00
(1)

1,6-Diphenyl-1,3,5-hexatriene is a highly conjugated hydrocarbon known for its exceptional photophysical properties, particularly in lipid environments. Its extended π-conjugation facilitates strong interactions with lipid membranes, promoting unique fluorescence characteristics. The compound exhibits notable solvatochromism, where its emission spectrum shifts in response to the lipid matrix, revealing insights into membrane dynamics and organization. Additionally, its ability to form J-aggregates in lipid layers can influence membrane fluidity and stability.

Sudan III

85-86-9sc-203761
sc-203761B
25 g
100 g
$43.00
$137.00
2
(1)

Sudan III is a synthetic dye characterized by its strong affinity for lipid environments, primarily due to its hydrophobic nature. This compound exhibits significant partitioning behavior, allowing it to intercalate within lipid bilayers, which can alter membrane properties. Its distinct colorimetric response to lipid composition enables the visualization of membrane structures. Furthermore, Sudan III's interactions with lipids can influence phase transitions, providing insights into membrane dynamics and organization.

Sudan Orange G

2051-85-6sc-215924
sc-215924A
25 g
100 g
$47.00
$173.00
(0)

Sudan Orange G is a synthetic dye known for its pronounced lipophilicity, which facilitates its incorporation into lipid-rich environments. This compound demonstrates unique interactions with lipid membranes, leading to alterations in membrane fluidity and permeability. Its vibrant coloration allows for effective visualization of lipid distribution, while its ability to form aggregates in lipid matrices can impact local microenvironments. Additionally, Sudan Orange G's kinetic behavior in lipid systems reveals insights into molecular mobility and phase behavior.

Nile Blue chloride

2381-85-3sc-295928
sc-295928A
5 g
25 g
$48.00
$171.00
(0)

Nile Blue chloride is a synthetic dye characterized by its affinity for lipid environments, enabling it to intercalate within lipid bilayers. This compound exhibits unique electrostatic interactions with phospholipid head groups, influencing membrane dynamics and stability. Its distinct spectral properties allow for the observation of lipid organization, while its aggregation behavior in lipid matrices can modify local physicochemical properties. The dye's interaction kinetics provide valuable insights into lipid phase transitions and molecular interactions.

Solvent Blue 37

3861-73-2sc-215891
5 g
$158.00
(0)

Acid Blue 92 is a synthetic dye known for its strong affinity for lipid-rich environments, where it can form stable complexes with lipid molecules. Its unique hydrophobic interactions facilitate incorporation into lipid membranes, altering their fluidity and permeability. The dye exhibits distinct fluorescence characteristics, enabling the study of lipid organization and dynamics. Additionally, its ability to modulate lipid phase behavior offers insights into membrane biophysics and molecular interactions.