KRTAP4-1 Inhibitors
Keratin-associated proteins (KRTAPs) are critical in hair fiber formation, with KRTAP4-1 being a specific subtype. KRTAP4-1 inhibitors are chemicals that can influence KRTAP4-1, albeit indirectly. These chemicals primarily modulate hair growth or the hair cycle, affecting various associated pathways that, in turn, may impact KRTAP4-1 expression or function.
Notably, many of these inhibitors, like EGF receptor inhibitors, play roles in keratinocyte biology, a crucial component of hair follicle structures. Then there are agents like DHT blockers, which target hormonal pathways influencing hair loss and growth. Each of these compounds, by intervening in specific stages or mechanisms of hair growth, can influence the expression or function of KRTAP4-1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Immunosuppressive drug that can promote hair growth possibly by targeting hair follicle immune privilege; this could indirectly affect KRTAP4-1 expression. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
These inhibit the EGF receptors, which can regulate keratinocyte proliferation and differentiation, potentially influencing KRTAP4-1. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Impacts keratinocyte proliferation and differentiation. Changes in the differentiation pathway could indirectly modulate KRTAP4-1. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
An aldosterone antagonist that can be used off-label for hair growth, potentially influencing KRTAP4-1 expression indirectly. | ||||||
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $62.00 $260.00 | 21 | |
An antifungal that's been suggested to have anti-androgenic effects and can be used for hair loss. This could indirectly affect KRTAP4-1. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $103.00 | 3 | |
By blocking the conversion of testosterone to DHT, it can promote hair growth and potentially influence KRTAP4-1. | ||||||
Bimatoprost | 155206-00-1 | sc-205224 sc-205224A | 1 mg 5 mg | $118.00 $455.00 | 1 | |
Another prostaglandin analog promoting hair growth, potentially influencing KRTAP4-1. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Rho-associated protein kinase (ROCK) inhibitor; affects hair growth and hair follicle morphogenesis, possibly impacting KRTAP4-1. | ||||||