KIAA2013_2510039O18Rik Activators
KIAA2013 Activators are a class of chemical compounds that either directly or indirectly enhance the functional activity of KIAA2013, a protein known to interact with Rac1-activated pathways. Some of these activators, such as Epidermal Growth Factor (EGF), Forskolin, and Isoproterenol, activate receptor tyrosine kinases and adenylate cyclase respectively. These actions stimulate the Rac1 GTPase, which in turn enhances the function of KIAA2013 due to its involvement in these pathways. Other KIAA2013 activators, including Uridine Triphosphate (UTP), Nicotinamide Adenine Dinucleotide (NAD), and Thrombin, function by increasing intracellular Ca2+ levels which can enhance the activity of Rac1, and thereby indirectly enhance KIAA2013 function.
Additional activators, like Sphingosine-1-Phosphate (S1P) and Lysophosphatidic Acid (LPA), activate their respective G protein-coupled receptors to stimulate Rac1 activity, indirectly enhancing the function of KIAA2013. Acetylcholine, Adenosine Triphosphate (ATP), and Endothelin-1 (ET-1) also contribute to the activation of KIAA2013 by increasing intracellular Ca2+ levels and subsequently activating Rac1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic receptor agonist, stimulates adenylate cyclase and increases cAMP levels, thereby enhancing Rac1 activity and subsequently the function of KIAA2013. | ||||||
Uridine-5′-triphosphate, Trisodium Salt | 19817-92-6 | sc-301964 sc-301964A | 50 mg 1 g | $88.00 $120.00 | 2 | |
UTP can activate P2Y receptors leading to PLC activation. PLC can enhance Rac1 activity which can in turn enhance the function of KIAA2013. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD stimulates CD38 which leads to the production of cyclic ADP-ribose. This increases intracellular Ca2+ that subsequently can enhance Rac1 activity and thereby the function of KIAA2013. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin can activate PAR receptors that can increase intracellular Ca2+, leading to Rac1 activation and subsequent enhancement of KIAA2013 function. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P activates sphingosine-1-phosphate receptors, which can stimulate Rac1 activity and indirectly enhance the function of KIAA2013. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA, through its G protein-coupled receptors, can stimulate Rac1 activity and indirectly enhance the function of KIAA2013. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
ATP activates P2Y receptors, leading to an increase in intracellular Ca2+ levels, which subsequently enhances the function of KIAA2013 by activating Rac1. | ||||||