Date published: 2025-9-15

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Ion Pair Reagents

Santa Cruz Biotechnology now offers a broad range of ion pair reagents for use in various applications. Ion pair reagents are essential in chromatography, particularly in high-performance liquid chromatography (HPLC), where they enhance the separation of ionic and highly polar compounds. These reagents work by forming ion pairs with the analyte ions, thereby increasing their hydrophobicity and retention on reversed-phase columns. This process improves the separation efficiency and resolution of complex mixtures, which is crucial in analyzing biological samples and environmental pollutants. Researchers use ion pair reagents to achieve better peak shapes, enhanced selectivity, and increased sensitivity in their chromatographic analyses. These reagents are particularly valuable for separating and quantifying small ions, peptides, and nucleotides, providing precise and reproducible results. By offering a comprehensive selection of high-quality ion pair reagents, Santa Cruz Biotechnology supports advanced research in analytical chemistry, biochemistry, and environmental science. These products empower scientists to optimize their chromatographic conditions, leading to improved analytical performance and reliable identification and quantification of target compounds. View detailed information on our available ion pair reagents by clicking on the product name.

Items 11 to 20 of 33 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Sodium 1-octanesulfonate monohydrate

207596-29-0sc-250993
10 g
$115.00
(0)

Sodium 1-octanesulfonate monohydrate serves as a versatile ion pair reagent, notable for its capacity to stabilize charged species in organic solvents. The extended octane chain enhances hydrophobic interactions, facilitating the solubilization of ionic compounds. Its sulfonate moiety engages in strong electrostatic interactions, which can significantly alter reaction kinetics and pathways. This compound's unique structure allows for tailored manipulation of ion pairing, optimizing conditions for various chemical reactions.

Dihexylamine acetate solution

366793-17-1sc-257348
sc-257348A
25 ml
1 L
$140.00
$525.00
(1)

Dihexylamine acetate solution functions as an effective ion pair reagent, characterized by its ability to form stable complexes with ionic species in nonpolar environments. The dual hydrophobic hexyl chains promote significant solvation effects, enhancing the mobility of ions. Its acetate component facilitates unique hydrogen bonding interactions, influencing reaction dynamics and selectivity. This compound's distinctive molecular architecture allows for precise control over ion pairing, thereby optimizing reaction conditions in diverse chemical processes.

Sodium 2-naphthalenesulfonate

532-02-5sc-250997
25 g
$61.00
(0)

Sodium 2-naphthalenesulfonate serves as a versatile ion pair reagent, notable for its ability to stabilize ionic species through π-π stacking interactions and hydrophobic effects. The naphthalene moiety enhances solubility in organic solvents, promoting efficient ion transport. Its sulfonate group contributes to strong electrostatic interactions, facilitating the formation of ion pairs that can significantly alter reaction kinetics and selectivity in various chemical environments.

Sodium 1-butanesulfonate

2386-54-1sc-250988
sc-250988A
2.5 g
10 g
$38.00
$114.00
(0)

Sodium 1-butanesulfonate functions effectively as an ion pair reagent, characterized by its unique ability to enhance solubility in polar solvents while maintaining ionic stability. The butyl chain introduces hydrophobic interactions, which can influence the solvation dynamics of ions. This compound promotes the formation of ion pairs through its sulfonate group, leading to altered reaction pathways and improved selectivity in various chemical processes, particularly in complex mixtures.

Sodium hexanesulfonate

2832-45-3sc-258165
5 g
$81.00
(0)

Sodium hexanesulfonate serves as a versatile ion pair reagent, notable for its capacity to stabilize charged species in solution. The extended hexyl chain enhances hydrophobic interactions, facilitating the formation of ion pairs that can modify reaction kinetics. Its sulfonate moiety plays a crucial role in solvation, allowing for selective binding and improved ion mobility. This unique behavior can lead to enhanced efficiency in various analytical and synthetic applications, particularly in challenging environments.

Dodecyltrimethylammonium hydrogen sulfate

103999-25-3sc-234841
10 g
$246.00
(0)

Dodecyltrimethylammonium hydrogen sulfate functions as a distinctive ion pair reagent, characterized by its long hydrophobic dodecyl chain that promotes strong van der Waals interactions. This structure enhances the solubility of ionic compounds, enabling effective stabilization of charged species. The quaternary ammonium group facilitates unique electrostatic interactions, influencing reaction pathways and kinetics. Its ability to form stable ion pairs can significantly alter the dynamics of chemical processes, making it a valuable tool in various analytical contexts.

Tetramethylammonium chloride

75-57-0sc-251199
sc-251199A
5 g
100 g
$20.00
$34.00
(0)

Tetramethylammonium chloride serves as a notable ion pair reagent, distinguished by its compact, symmetrical structure that enhances solvation dynamics. The quaternary ammonium moiety promotes strong ionic interactions, facilitating the formation of stable ion pairs. This stability can modify reaction kinetics and pathways, allowing for selective ion transport and enhanced reactivity in various chemical environments. Its unique properties make it an effective medium for studying ionic interactions and complexation phenomena.

Sodium octyl sulfate

142-31-4sc-251036
sc-251036A
1 g
5 g
$36.00
$141.00
(0)

Sodium octyl sulfate is an effective ion pair reagent characterized by its amphiphilic nature, which promotes unique molecular interactions in solution. The long hydrophobic octyl chain enhances solubilization of nonpolar compounds, while the sulfate group facilitates strong ionic interactions. This duality allows for the stabilization of ion pairs, influencing reaction kinetics and selectivity. Its ability to modulate electrostatic interactions makes it valuable for exploring complexation and aggregation behaviors in various chemical systems.

Sodium 1,2-ethanedisulfonate

5325-43-9sc-253574
25 g
$86.00
(0)

Sodium 1,2-ethanedisulfonate serves as a versatile ion pair reagent, distinguished by its dual sulfonate groups that enhance solubility and ionic strength in aqueous environments. This compound effectively stabilizes charged species through strong electrostatic interactions, facilitating the formation of ion pairs. Its unique structure promotes specific molecular pathways, influencing reaction dynamics and selectivity in various chemical processes, while also enabling the study of solvation effects and molecular aggregation.

Sodium 1-undecanesulfonate

5838-34-6sc-258160
1 g
$40.00
(0)

Sodium 1-undecanesulfonate functions as an effective ion pair reagent, characterized by its long hydrophobic alkyl chain that enhances lipophilicity and promotes micelle formation in solution. This unique structure allows for selective solvation of ions, influencing reaction kinetics and enhancing the stability of transient species. Its ability to modulate ionic interactions and promote aggregation makes it a valuable tool for studying complexation and phase behavior in various chemical systems.