IFN-α5 Activators
IFN-α5 Activity Enhancers; These compounds primarily function as immunomodulators or immunostimulants, activating different pathways that lead to increased production or efficacy of IFN-α5.
Compounds like Poly(I:C), Imiquimod, and Resiquimod work through toll-like receptors (TLR3, TLR7, and TLR8), which are part of the innate immune system and play a crucial role in the early response to viral infections. Activation of these receptors leads to the upregulation of type I interferons, including IFN-α5, which are key players in antiviral defense. Other compounds, such as CpG ODN 1826, Pidotimod, and Amlexanox, also modulate immune responses, though through slightly different pathways. These agents enhance the body's innate and adaptive immune responses, which can indirectly lead to increased IFN-α5 activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
A synthetic analog of double-stranded RNA that acts as a potent inducer of type I interferons, including IFN-α5, by stimulating toll-like receptor 3 (TLR3). | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
A topical immunomodulator that activates immune cells via toll-like receptor 7 (TLR7), leading to increased production of type I interferons, including IFN-α5. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
An agonist of TLR7 and TLR8, Resiquimod enhances the production of type I interferons, potentially affecting IFN-α5 levels. | ||||||
Gardiquimod | 1020412-43-4 | sc-221663 sc-221663A sc-221663B sc-221663C sc-221663D sc-221663E sc-221663F | 25 mg 50 mg 100 mg 250 mg 5 g 10 g 25 g | $157.00 $282.00 $516.00 $1177.00 $20138.00 $32779.00 $70753.00 | 1 | |
A selective TLR7 agonist that can indirectly increase the levels of type I interferons, including IFN-α5. | ||||||
Amlexanox | 68302-57-8 | sc-217630 | 10 mg | $160.00 | 2 | |
Traditionally used to treat aphthous ulcers, it can modulate immune responses and may influence IFN-α5 activity. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
An antiviral drug that has been shown to enhance the efficacy of interferons in certain contexts. | ||||||
Levamisole Hydrochloride | 16595-80-5 | sc-205730 sc-205730A | 5 g 10 g | $43.00 $68.00 | 18 | |
An immunomodulator that can influence the production and activity of type I interferons. | ||||||