IFN-α2 Activators
The class of chemicals identified as indirect activators of IFN-α2 encompasses a diverse range of compounds primarily involved in stimulating the immune system. These chemicals can enhance IFN-α2 activity or its production by acting on various immune cells or signaling pathways. The importance of IFN-α2 in antiviral defense, and immune regulation makes the understanding of these indirect activators crucial.
Compounds such as Poly(I:C), Imiquimod, and Resiquimod function as immune response modifiers by mimicking the presence of viral or bacterial components, thereby stimulating the body's innate immune response. This activation can lead to increased production of cytokines, including IFN-α2. These compounds are known for their ability to enhance antiviral and antitumor immune responses, which is partly mediated through the induction of IFN-α2. The Bacillus Calmette-Guerin (BCG) vaccine, known for its broad immunostimulatory effects, can also lead to an increase in IFN-α2 production as part of the general activation of the immune system. Immunomodulatory agents like Levamisole and Isoprinosine (Inosine Pranobex) are included due to their roles in enhancing various aspects of the immune response, which could include the stimulation of IFN-α2 production.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
A synthetic analog of double-stranded RNA, known to stimulate the immune response and potentially enhance IFN-α2 production. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
A topical immunomodulator that can induce the production of IFN-α2 as part of its antiviral and antitumor activities. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
A chemical similar to Imiquimod, known to stimulate immune responses, potentially leading to increased IFN-α2 production. | ||||||
Gardiquimod | 1020412-43-4 | sc-221663 sc-221663A sc-221663B sc-221663C sc-221663D sc-221663E sc-221663F | 25 mg 50 mg 100 mg 250 mg 5 g 10 g 25 g | $157.00 $282.00 $516.00 $1177.00 $20138.00 $32779.00 $70753.00 | 1 | |
A TLR7 agonist that can stimulate innate immune responses, potentially enhancing IFN-α2 production. | ||||||
Levamisole Hydrochloride | 16595-80-5 | sc-205730 sc-205730A | 5 g 10 g | $43.00 $68.00 | 18 | |
An immunomodulatory agent that can enhance immune responses, potentially leading to increased production of IFN-α2. | ||||||
Isoprinosine | 36703-88-5 | sc-279232 sc-279232A sc-279232B | 10 mg 100 mg 1 g | $120.00 $210.00 $270.00 | ||
An immunostimulant that can enhance various aspects of the immune response, possibly including the production of IFN-α2. | ||||||