Ichthyin Inhibitors form a specialized chemical class of compounds that have garnered scientific interest for their potential to selectively modulate the activity of the ichthyin protein, also known as NIPAL4. Ichthyin is a protein associated with skin disorders known as ichthyoses, a group of rare genetic conditions characterized by impaired skin barrier function and abnormal scaling of the skin. The chemical class of Ichthyin Inhibitors is designed to interact with specific regions or binding sites within the ichthyin protein. By engaging with ichthyin, these inhibitors aim to modulate its functional activity, which might include regulating cellular processes relevant to skin barrier function, lipid metabolism, or epidermal differentiation. Inhibiting ichthyin's activity could potentially offer insights into the underlying molecular mechanisms contributing to the pathogenesis of ichthyosis-related skin disorders, thus contributing to our understanding of skin biology and dermatological health.
However, it is essential to underscore that the field of Ichthyin Inhibitors is continuously evolving, and comprehensive investigations are necessary to fully elucidate the precise mechanisms of action and potential selectivity of these compounds for ichthyin. As researchers delve deeper into the functional implications of ichthyin inhibition, the ongoing exploration of Ichthyin Inhibitors holds promise in advancing our understanding of this protein's biological significance and could lead to novel discoveries and future research avenues in skin biology and related fields.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Found in vitamin A and can modulate gene expression and cellular differentiation. | ||||||
Tazarotene | 118292-40-3 | sc-220193 | 10 mg | $103.00 | ||
Tazarotene is a prodrug for tazarotenic acid with selective affinity for RARβ and RARγ | ||||||
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $54.00 $245.00 | 6 | |
Bexarotene is a selective agonist of retinoid X receptors | ||||||
Acitretin | 55079-83-9 | sc-210754 | 25 mg | $148.00 | 1 | |
Acitretin is a synthetic retinoid - the major metabolite of etretinate | ||||||
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $377.00 $2602.00 | ||
A form of vitamin A with potential biological activities. | ||||||
Adapalene | 106685-40-9 | sc-203803 sc-203803A | 10 mg 50 mg | $65.00 $325.00 | 2 | |
Adapalene is a retinoic acid analog and apoptosis inducer | ||||||
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $74.00 $118.00 | 8 | |
13-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
An immunosuppressive and anti-inflammatory agent. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporin A is a fungal metabolite calcineurin and mitochondrial permeability transition pore opening inhibitor. | ||||||
Calcipotriol | 112965-21-6 | sc-203537 sc-203537A | 10 mg 50 mg | $199.00 $816.00 | 4 | |
Calcipotriol is vitamin D3 analog | ||||||