HTF9C Activators
HTF9C is an enzyme involved in tRNA (transfer RNA) modification, particularly the methylation of adenosine residues at position 58, crucial for the stability and fidelity of tRNA molecules. One group of potential HTF9C activators comprises molecules involved in one-carbon metabolism, such as S-Adenosyl Methionine (SAM), Folate, and Vitamin B12. SAM serves as a primary methyl donor in cellular methylation reactions, including tRNA modification. Folate and Vitamin B12 are essential for one-carbon metabolism and are involved in the synthesis of SAM, indirectly influencing HTF9C by ensuring the availability of methyl groups required for tRNA methylation reactions. Additionally, amino acids like Methionine and Serine are building blocks of SAM, potentially enhancing HTF9C activity by participating in the synthesis of this methyl donor.
Another group of compounds with HTF9C activation potential includes ribonucleosides like Adenosine, which are fundamental in RNA synthesis and structure. Ensuring an adequate pool of ribonucleosides in the cell can indirectly support HTF9C by providing the necessary substrates for tRNA modification reactions. Furthermore, Methylthioadenosine (MTA), a product of tRNA modification reactions, can signal the need for increased tRNA modification and potentially influence HTF9C activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
SAM is a methyl donor in cellular methylation reactions. It can potentially indirectly activate HTF9C by providing methyl groups for tRNA modification reactions, a process in which HTF9C is involved. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Ribonucleosides are building blocks of RNA. Their availability in the cell can indirectly influence HTF9C by ensuring a sufficient pool of substrates for tRNA modification reactions. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $73.00 | 2 | |
Folate is involved in one-carbon metabolism and can indirectly impact HTF9C by contributing to the synthesis of methyl donors like SAM, which are crucial for tRNA modification reactions. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $60.00 $90.00 $325.00 $1155.00 $3851.00 $10056.00 | 2 | |
Vitamin B12 is essential for various cellular processes, including methionine synthesis. It can indirectly influence HTF9C by contributing to the availability of SAM, which is required for tRNA modification. | ||||||
L-Methionine | 63-68-3 | sc-394076 sc-394076A sc-394076B sc-394076C sc-394076D sc-394076E | 25 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $37.00 $57.00 $151.00 $577.00 $1103.00 | ||
Methionine is an amino acid and a precursor to SAM. It can potentially indirectly activate HTF9C by participating in the synthesis of SAM, which is crucial for tRNA modification reactions. | ||||||
L-Serine | 56-45-1 | sc-397670 sc-397670A sc-397670B sc-397670C sc-397670D | 1 g 100 g 1 kg 5 kg 10 kg | $20.00 $133.00 $546.00 $1224.00 $2040.00 | ||
Serine is an amino acid that plays a role in one-carbon metabolism. It can indirectly affect HTF9C by contributing to the synthesis of methyl donors, including SAM. | ||||||
5′-Deoxy-5′-methylthioadenosine | 2457-80-9 | sc-202427 | 50 mg | $122.00 | 1 | |
MTA is a product of tRNA modification reactions. Its accumulation can potentially signal the need for increased tRNA modification, indirectly affecting HTF9C. | ||||||
Adenosine phosphate(Vitamin B8) | 61-19-8 | sc-278678 sc-278678A | 50 g 100 g | $160.00 $240.00 | ||
Providing an adequate supply of nucleotide precursors can indirectly support HTF9C by ensuring the availability of tRNA building blocks. | ||||||