Date published: 2025-9-25

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Heterobifunctional Crosslinkers

Santa Cruz Biotechnology now offers a broad range of heterobifunctional crosslinkers for use in various applications. Heterobifunctional crosslinkers are versatile chemical reagents that possess two different reactive groups, allowing them to link two distinct molecules or surfaces. These crosslinkers are crucial in scientific research for studying and manipulating molecular interactions, creating conjugates, and developing advanced biomaterials. Researchers utilize heterobifunctional crosslinkers to investigate protein-protein, protein-DNA, and protein-ligand interactions, providing insights into cellular signaling pathways, structural biology, and enzymatic functions. They are also used to immobilize biomolecules on various surfaces for biosensor development, drug delivery systems, and diagnostic assays. The ability to selectively and efficiently join different molecules makes these crosslinkers invaluable for designing complex molecular architectures and enhancing the functionality of biomaterials. By providing a comprehensive selection of high-quality heterobifunctional crosslinkers, Santa Cruz Biotechnology supports cutting-edge research in biochemistry, molecular biology, and materials science. These products enable scientists to achieve precise and reproducible results, driving advancements in our understanding of molecular interactions and the development of innovative biotechnological applications. View detailed information on our available heterobifunctional crosslinkers by clicking on the product name.

Items 41 to 50 of 56 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester

211236-68-9sc-213588
sc-213588A
100 mg
250 mg
$320.00
$540.00
(0)

11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester is a heterobifunctional reagent featuring a maleimide and a sulfo-N-succinimidyl ester group. The maleimide moiety exhibits high specificity for thiol groups, enabling stable covalent bond formation, while the sulfo-N-succinimidyl ester facilitates efficient coupling with amines. This dual reactivity allows for precise bioconjugation, enhancing the ability to create complex biomolecular architectures and tailored interactions in diverse environments.

11-Maleimidoundecanoic Acid Hydrazide

359436-62-7sc-208849
10 mg
$330.00
(0)

11-Maleimidoundecanoic Acid Hydrazide is a heterobifunctional compound characterized by its unique reactivity profile. The hydrazide group allows for selective conjugation with carbonyl-containing compounds, while the maleimide moiety provides a strong affinity for thiol groups. This dual functionality enables the formation of stable linkages and promotes intricate molecular assemblies. Its distinct reactivity pathways facilitate the development of customized biomolecular constructs, enhancing specificity in various applications.

3-(Benzophenone-4-carboxamido)-2-maleimidopropanoic acid

887352-68-3sc-209472
5 mg
$360.00
(0)

3-(Benzophenone-4-carboxamido)-2-maleimidopropanoic acid is a heterobifunctional compound distinguished by its ability to engage in selective cross-linking reactions. The carboxamido group enhances solubility and reactivity, while the maleimide moiety exhibits a strong preference for thiol groups, enabling efficient conjugation. This compound's unique interaction dynamics facilitate the formation of robust molecular networks, allowing for tailored modifications in complex biochemical environments.

4-(Maleimidomethyl)cyclohexane-1-carbonyl-1-(tert-butyl)carbazate

887406-71-5sc-216696
25 mg
$330.00
(0)

4-(Maleimidomethyl)cyclohexane-1-carbonyl-1-(tert-butyl)carbazate is a heterobifunctional compound characterized by its dual reactivity. The maleimide group selectively reacts with thiols, promoting targeted conjugation, while the carbazate moiety enhances stability and solubility. This compound's unique structural features enable it to form stable linkages in diverse environments, facilitating intricate molecular assemblies and enabling precise modifications in various chemical contexts.

N-Succinimidyloxycarbonylheptyl Methanethiosulfonate

887407-50-3sc-219229
10 mg
$330.00
(0)

N-Succinimidyloxycarbonylheptyl Methanethiosulfonate is a heterobifunctional reagent distinguished by its ability to engage in selective thiol reactions through its methanethiosulfonate group, which forms stable thioether bonds. The succinimidyl moiety enhances reactivity towards amines, allowing for efficient conjugation. This compound's unique design promotes versatile cross-linking and functionalization, making it suitable for creating complex molecular architectures and facilitating specific biochemical interactions.

N-Succinimidyloxycarbonylpentadecyl Methanethiosulfonate

887407-52-5sc-219230
10 mg
$280.00
(0)

N-Succinimidyloxycarbonylpentadecyl Methanethiosulfonate is a heterobifunctional compound characterized by its dual reactivity. The methanethiosulfonate group enables robust thiol-mediated reactions, forming durable thioether linkages, while the succinimidyl component facilitates amine coupling. This unique combination allows for precise molecular modifications and the formation of intricate networks, enhancing the potential for tailored interactions in various biochemical contexts. Its structural features promote efficient reaction kinetics, making it a versatile tool for advanced chemical synthesis.

N-Succinimidyloxycarbonylundecyl Methanethiosulfonate

887407-54-7sc-212286
10 mg
$360.00
(0)

N-Succinimidyloxycarbonylundecyl Methanethiosulfonate is a heterobifunctional reagent distinguished by its ability to engage in selective thiol and amine reactions. The methanethiosulfonate moiety promotes stable thioether bond formation, while the succinimidyl group enhances reactivity towards amines, enabling targeted conjugation. This compound's unique structural attributes facilitate rapid reaction kinetics and enable the creation of complex molecular architectures, making it a powerful agent for diverse synthetic applications.

3-(Maleimidopropane-1-carbonyl-1-(tert-butyl)carbazate

1076198-38-3sc-357585
100 mg
$330.00
(0)

3-(Maleimidopropane-1-carbonyl-1-(tert-butyl)carbazate is a heterobifunctional compound characterized by its dual reactivity towards thiols and amines. The maleimide group facilitates efficient thiol conjugation, forming stable thioether linkages, while the carbazate moiety enhances nucleophilic attack by amines. This compound exhibits favorable reaction kinetics, allowing for precise control in synthetic pathways, and its unique structure supports the formation of intricate molecular networks.

11-Maleimidoundecane-1-carbonyl-1-(t-butyl)carbazate

1076198-39-4sc-213587
25 mg
$300.00
(0)

11-Maleimidoundecane-1-carbonyl-1-(t-butyl)carbazate is a heterobifunctional compound distinguished by its ability to engage in selective reactions with both thiols and amines. The maleimide functionality promotes robust thiol coupling, yielding stable thioether bonds, while the carbazate segment enhances reactivity with amines through nucleophilic substitution. This compound's structural attributes enable the formation of complex molecular architectures, facilitating diverse synthetic strategies and enhancing reaction specificity.

Maleimide-PEG2-NHS

955094-26-5sc-397274
sc-397274A
50 mg
250 mg
$178.00
$510.00
(0)

Maleimide-PEG2-NHS is a heterobifunctional linker characterized by its dual reactivity towards amines and thiols. The maleimide group enables efficient thiol conjugation, forming stable thioether linkages, while the NHS ester facilitates rapid and selective amine reactions, promoting the formation of stable amide bonds. Its PEG spacer enhances solubility and biocompatibility, allowing for versatile applications in bioconjugation and the construction of multifunctional biomolecules.