Date published: 2026-4-10

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GPR12 Activators

Santa Cruz Biotechnology now offers a broad range of GPR12 Activators for use in various applications. GPR12, a member of the G-protein coupled receptor (GPCR) family, is an orphan receptor that has gained significant interest in scientific research due to its diverse roles in cellular signaling and physiological processes. GPR12 Activators are small molecules or compounds that selectively bind to and activate this receptor, providing a powerful tool for explaining the receptor's function and regulation. Researchers utilize these activators in various experimental models to study the signaling pathways modulated by GPR12, which are crucial for understanding its role in cellular homeostasis, metabolism, and developmental processes. The activation of GPR12 by specific ligands can lead to the modulation of intracellular cyclic AMP levels, impacting various downstream signaling cascades. This makes GPR12 Activators invaluable in the study of receptor-ligand interactions and the broader GPCR signaling landscape. Additionally, these activators are essential in the development of biosensors and assays designed to monitor receptor activity, providing insights into the mechanisms of action and potential interactions with other cellular components. As research continues to explore the diverse functions of GPR12, these activators serve as crucial tools in both basic and applied sciences, aiding in the discovery of novel biological pathways and targets. View detailed information on our available GPR12 Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$165.00
$322.00
$570.00
$907.00
$1727.00
7
(1)

D-erythro-Sphingosine-1-phosphate acts as a GPR12 ligand, engaging in selective receptor binding that triggers distinct intracellular signaling cascades. Its structural conformation allows for effective interaction with the receptor's active site, promoting downstream effects on cellular processes. The compound's amphipathic nature facilitates its integration into lipid bilayers, enhancing its bioavailability and influencing cellular dynamics. Its unique interaction profile contributes to the modulation of various signaling pathways, underscoring its role in cellular communication.