GlyT2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bitopertin | 845614-11-1 | sc-503853 | 50 mg | $9500.00 | ||
Bitopertin is a GlyT2 inhibitor which acts by increasing glycine levels in the brain, which enhances the activity of NMDA receptors involved in synaptic transmission. | ||||||
N-Arachidonoyl glycine (solution in ethanol) | 179113-91-8 | sc-203149 | 5 mg | $101.00 | ||
N-Arachidonoyl glycine, a glycine transporter 2 (GlyT2) modulator, showcases unique molecular interactions that influence synaptic transmission. Its structural features allow for selective binding to GlyT2, altering the transport kinetics and enhancing glycine uptake. The compound's hydrophobic regions promote interactions with lipid membranes, potentially affecting membrane fluidity. Additionally, its ethanol solubility aids in facilitating rapid distribution within biological systems, impacting its functional dynamics. | ||||||
ALX-1393 | 949164-09-4 | sc-300191 sc-300191A | 500 µg 1 mg | $120.00 $180.00 | 1 | |
ALX-1393 acts as a selective modulator of glycine transporter 2 (GlyT2), exhibiting distinct binding affinities that influence neurotransmitter regulation. Its unique structural conformation enables specific interactions with the transporter, modulating its activity and altering glycine reuptake dynamics. The compound's ability to engage in hydrogen bonding and hydrophobic interactions enhances its stability in various environments, potentially affecting its reactivity and transport efficiency across cellular membranes. | ||||||
N-Arachidonoyl glycine | 179113-91-8 | sc-362169 sc-362169A | 5 mg 25 mg | $112.00 $187.00 | 2 | |
N-Arachidonoyl glycine serves as a potent modulator of glycine transporter 2 (GlyT2), characterized by its unique fatty acid backbone that facilitates specific interactions with the transporter. This compound influences glycine transport kinetics through allosteric modulation, altering the conformational dynamics of GlyT2. Its amphipathic nature promotes interactions with lipid membranes, potentially enhancing its bioavailability and influencing membrane fluidity, which may impact cellular signaling pathways. | ||||||