Date published: 2025-10-15

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GDF-9 Activators

GDF-9 activators in this context are chemicals that can indirectly influence the activity or expression of GDF-9, a growth factor critical for female fertility. The modulation of GDF-9 by these compounds is mediated through their impact on cellular signaling pathways, gene expression, and the ovarian microenvironment. Retinoic acid, known for its role in differentiation and gene expression, may indirectly affect GDF-9 expression in ovarian tissues. Follistatin and activin A, both involved in the regulation of reproductive processes, can modulate the ovarian microenvironment and GDF-9 activity.

BMP-4, as a member of the same superfamily as GDF-9, plays a role in ovarian follicle development and could interact with GDF-9 signaling pathways. Estradiol and IGF-1, important regulators of ovarian function, may also influence GDF-9 activity. Forskolin, by increasing cAMP levels, and vitamin D3, with its roles in gene regulation, might impact GDF-9 expression. DHEA, as a steroid precursor, can influence ovarian function and GDF-9 expression. Metformin can affect ovarian physiology, which might include GDF-9 activity. Natural compounds like EGCG and curcumin, known for their broad effects on cellular signaling, may also indirectly influence GDF-9.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid influences gene expression and differentiation in various tissues, potentially affecting GDF-9 expression.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

Estradiol, a key estrogen, can modulate various reproductive processes and potentially influence GDF-9 expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin raises cAMP levels, which could influence gene expression and signaling pathways relevant to GDF-9.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D3 has roles in gene regulation and could potentially impact GDF-9 expression in ovarian tissues.

DHEA

53-43-0sc-202573
10 g
$109.00
3
(1)

DHEA, a precursor to sex steroids, can influence ovarian function and possibly GDF-9 expression.

Metformin-d6, Hydrochloride

1185166-01-1sc-218701
sc-218701A
sc-218701B
1 mg
5 mg
10 mg
$286.00
$806.00
$1510.00
1
(1)

Metformin can influence ovarian physiology, particularly in the context of polycystic ovary syndrome, and might affect GDF-9.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG can modulate various signaling pathways, potentially impacting GDF-9 activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has multiple effects on cellular signaling and could indirectly influence GDF-9 expression.